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All Journal Mutiara Medika: Jurnal Kedokteran dan Kesehatan Scientia Psychiatrica Journal of Community Health and Preventive Medicine (JOCHAPM)
Budi Pratiti
Department Of Psychiatry, Faculty Of Medicine, Public Health And Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia
Environmental Science Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health

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Journal : Scientia Psychiatrica

 1 
Comorbid of Obsessive-Compulsive Disorder and Schizophrenia: A Case Report Budi Pratiti; Jimmi Aritonang
Scientia Psychiatrica Vol. 1 No. 1 (2020): Scientia Psychiatrica
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (104.855 KB) | DOI: 10.37275/scipsy.v1i1.1

Abstract

Introduction: Schizophrenia was a chronic mental disorder that is marked by abnormal social and impairment in reality testing ability. A person diagnosed with schizophrenia may experience a number of symptoms including hallucinations, delusions, disorganized thinking, bizarre speech, and behavior. Obsessive-compulsive disorder is well known as a comorbid of schizophrenia. Comorbid OCD will affect the treatment of schizophrenia and other mental disorder. Case presentation: A 14-year-old student Muslim boy from a rural household in Central Java, Indonesia who had 8 years of formal education and live with his parent was brought to the emergency department of a mental hospital by his parents who reported a one-year history of excessive washing of his body, soaking his body for hours in the bathtub and sleep in the bathroom. The patient first fell in January 2019; over a six-month period, he became progressively deteriorated, lost interest in his hobby, stopped going to school, and reduced his food intake. After one week treatment of with venlafaxine and risperidone, He became more cooperative and interactive with the examiner. At that time, the patient reported delusional beliefs about contamination and paranoid delusion, and there were several indications of formal thought disorder, including derailment, neologisms, concrete thinking, circumstantiality, and illogicality. An intelligence test revealed average intelligence (IQ=100). The total score of the Brief Psychiatric Rating Scale (BPRS) 3 dropped from 42 to 24, the score on the Yates-Brown Obsessive-Compulsive Symptoms (YBOCS)4 scale dropped from 24 to 18, and the score on the Global Assessment of Functioning scale (GAF)5 increased from 25 to 55. After discharge, the patient adhered to his medication regimen, and three months after discharge, his clinical improvement persisted; he was able to maintain his personal hygiene and take care of his daily needs, but he remained socially isolated and was unable to return to school. Conclusion: Obsessive-compulsive disorder and schizophrenia could happen together in one individual. The treatment should consider the underlying condition and cognitive function, especially if the patient is of productive age.
Haloperidol and Risperidone Induce Apoptosis Neuronal Cell: In vivo Study Ester G Panserga; Cecep S Kristanto; Budi Pratiti; Patricia Wulandari
Scientia Psychiatrica Vol. 1 No. 1 (2020): Scientia Psychiatrica
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (271.205 KB) | DOI: 10.37275/scipsy.v1i1.5

Abstract

Introduction: Antipsychotics are drugs that are widely prescribed for mental disorders, such as schizophrenia and psychosis. Recent in vitro studies show antipsychotics play a role in the initiation of neuronal cell apoptosis. This study aims to determine the effect of haloperidol and risperidone on neuronal cell apoptosis in Wistar white rats. Methods: Male Wistar rats aged 8 weeks (n = 30) were used in this study. Wistar rats were randomized into 6 groups. Group A: 5 Wistar rats as the control without induced schizophrenia, aquadest, and drugs. Group B: 5 Wistar-induced psychotic mice (using 30 mg / kgBB ketamine, intraperitoneal injection for 5 days) and aquadest. Group C: 5 rats were induced psychotic and were given haloperidol or 0.05 mg / kgBB orally, for 28 days. Group D: 5 mice were induced psychotic and were given haloperidol 0.1 mg/kg orally, for 28 days. Group E: 5 mice were induced psychotic and were given risperidone 0.05 mg / kgBB orally, for 28 days. Group F: 5 mice were induced psychotic and given risperidone 0.1 mg / kgBB orally, for 28 days. Apoptosis of neuronal cells in the ventral tegmental area was assessed by caspase-3 immunohistochemistry. The colored area will be calculated as a total percentage using the ImageJ program. Results: Risperidone and haloperidol increase caspase-3 activity, but haloperidol increases caspase- 3 activity more than risperidone. Conclusion: Risperidone and haloperidol induce apoptosis of neuronal cells and tardive dyskinesia in Wistar rats with psychotic models.
Tension Type Headache Comorbid with Moderate Depression: A Case Report Budi Pratiti
Scientia Psychiatrica Vol. 1 No. 2 (2020): Scientia Psychiatrica
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/scipsy.v1i2.12

Abstract

Tension type headaches (TTH) are generally caused by psychological factors and psychiatric disorders. Anxiety disorders and depression are more often associated with TTH than other disorders. This case report discusses the tension type headache accompanied by depression and its management. Miss Y, a 17 year old girl, 2nd in birth order, an undergraduate student living in a boarding house with her sister and coming from a low socio-economic background, came to Dr. Sardjito General hospital, Indonesia with complaints of severe headache since 2 months ago. Family history shows that there is a conflict in the patient's parents which makes the patient disappointed. In the examination found inferiority feelings, guilt and worry will disappoint everyone. She was then agreed to do cognitive behavior therapy and take medication according to doctor's orders. After 8 sessions, she developed confidence and started to carry out daily similar sessions at home. Tension-type headache in this case is accompanied by a dominant psychological factor. Collaboration between pharmacotherapy and psychotherapy in treating patients with tension type headaches is a fairly effective choice.
Psychodynamic Approach, Social Cognitive and Neurobiology Aspect of Tantrum Behaviour in Children Budi Pratiti
Scientia Psychiatrica Vol. 1 No. 3 (2020): Scientia Psychiatrica
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/scipsy.v1i3.18

Abstract

One form of emotional expression in the form of explosive anger in children is known as tantrum behaviour, which can be categorized as bad behaviour based on the perspective of some parents. This is very much related to the problem of child despair, which is caused by the way parents are not quite right in responding to tantrums, so the child reacts inappropriately. Parental responses make children increasingly undisciplined, even this provides opportunities for children to find certain ways to get their desires in a negative way. The child's inability to communicate is one aspect of tantrum studies. This communication is more translated as an expression of emotion and better known as tantrum. This article review will discuss temper tantrum behaviour in children along with a review of various theoretical points of view.
Co-Authors Afkar Aulia Cecep S Kristanto Ester G Panserga Jimmi Aritonang Meliya Nita Sari Patricia Wulandari Soewadi Soewadi Warih Andan Puspitosari