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All Journal Indonesian Journal of Urology Contagion: Scientific Periodical Journal of Public Health and Coastal Health Quantum Teknika Journal of Mechanical Design and Testing (JMDT) JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Academic Hospital Journal
Wikan Kurniawan
Division Of Urology, Department Of Surgery, Faculty Of Medicine, Public Health And Nursing, Universitas Gadjah Mada, Dr. Sardjito General Hospital, Jl. Kesehatan No. 1 Sinduadi, Mlati, Sleman PO 55281, Yogyakarta, Indonesia.
Automotive Engineering Chemical Engineering, Chemistry & Bioengineering Dentistry Engineering Health Professions Industrial & Manufacturing Engineering Mechanical Engineering Medicine & Pharmacology Nursing Public Health

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COMPARISON OF SERUM SODIUM, SERUM POTASSIUM, AND BLOOD HEMOGLOBIN CHANGES AFTER TRANSURETHRAL RESECTION OF THE PROSTATE BETWEEN IRRIGATION WITH NORMAL SALINE AND STERILE WATER Kurniawan, Wikan; Utomo, Trisula
Indonesian Journal of Urology Vol 18 No 2 (2011)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v18i2.74

Abstract

Objective: This study aims to know whether there are significant differences of blood sodium, potassium and hemoglobin level among patients post TURP who was irrigated by using normal saline and the sterile water. Material & Method: This is a single blind randomized clinical trial study performed from September 1, 2008 until August 31, 2009. Thirty-one subjects participated in this study. The subjects were divided into two groups, 14 subjects for normal saline (group I) irrigation and 17 subjects for sterilized water irrigation (group II). Results: There are statistically differences (p < 0,05) between hemoglobin concentrations changes in group I, and hemoglobin and sodium concentration changes in group II. There were no statistically differences (p > 0,05) in sodium and potassium changes in group I and potassium in group II. There are no statistically differences in hemoglobin, sodium, and potassium changes among two groups. Conclusion: Normal saline irrigant for irrigation after TURP give more stable post operative electrolyte profile compared to sterilized water. Keywords: TUR prostate, irrigation, serum sodium, potassium level differences.
Simulasi Pembebanan Komponen Bender pada Desain Mesin Begel Fabricator Menggunakan Software Autodesk Inventor 2020 Hariyanto, Satriawan Dini; Kurniawan, Wikan
Quantum Teknika : Jurnal Teknik Mesin Terapan Vol 2, No 2 (2021): April
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/jqt.v2i2.11581

Abstract

Stress analysis of the bender components in the design of the begel fabricator machine was carried out using FEA (Finite Element Analysis) with three variations of the constituent material parameters, namely 6061 aluminum, mild steel, and cast iron with a modulus of elasticity of 68.9 GPa, 220 GPa, 120.5 GPa, respectively. The test is carried out by a loading parameter 2520 MPa and fixed constraint. The maximum von misses stress and displacement obtained for each material parameter components using aluminum, mild steel, and cast iron are 17.78 MPa; 0.00765, 17.49 MPa; 0.00229, 17.62 MPa; 0.00427 respectively.
Design and Functionality of Monopolar Active Electrode for Medical Electrosurgery Purposes Satriawan Dini Hariyanto; Muslim Mahardika; Wikan Kurniawan
Journal of Mechanical Design and Testing Vol 1, No 1 (2019): Articles
Publisher : Departemen Teknik Mesin dan Industri, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (284.379 KB) | DOI: 10.22146/jmdt.46757

Abstract

Dua jenis operasi bedah medis yang dikenal saat ini adalah operasi bedah terbuka (conventional surgery) dan operasi endoskopis (endoscopic surgery). Operasi endoskopis dapat dilakukan dengan menggunakan laser dan electrosurgery. Permasalahan yang timbul saat operasi electrosurgery urologi adalah terbatasnya pemakaian komponen elektroda aktif tipe monopolar, yang hanya sebanyak empat kali operasi. Penelitian ini berisi pemaparan mengenai desain komponen elektroda aktif dan penjelasan fungsi dari tiap komponen elektroda yang telah penulis rancang
The changes of serum prostate specific antigen level in advanced prostate cancer patients undergoing palliative transurethral prostate resection Kurniawan, Wikan; Hardi, Hidayu Permata
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 16, No 1, (2025)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol16.Iss1.art4

Abstract

Background: Total Prostate specific antigen (tPSA) is a substance secreted by the prostate gland. It levels vary depending on the condition of the prostate and typically increase in response to increased prostate volume, cancer, infection, urinary retention and others. Conversely, tPSA levels decrease following a reduction in prostate volume. Palliative transurethral resection of the prostate (pTURP) is a procedure performed to relieve urinary retention in patients with metastatic prostate cancer who are not candidates for, or do not consent to, definitive treatment.Objective: This study aims to compare tPSA levels before and after pTURP in patients with advanced prostate cancer.Method: Using retrospective cross-sectional studyutilized patient medical records and laboratory results to compare pre- and post-operative tPSA levels. Data were collected from the UGM Academic Hospital's medical record between 2019 and 2022. Inclusion criteria included patients with available pre-operativeand post-operative tPSA levels and anatomic pathology results. Tumor characteristics were classified as cT3-4 or cN+ with any PSA level and any ISUP grade. Patients presented with symptoms such as urinary obstruction, pelvic pain, and/or haematuria, and all diagnoses were confirmed via prostate biopsy. Data were analyzed using the Mann-Whitney U test.Results: A total of 40 patients met the inclusion criteria. The mean average age was 72.45 years. The average resection time was 60.42 ± 5.41 minutes, and the mean resected tissue weight was 27.50 ± 8.06 grams. Complications occurred in 30% of patients within 90 days post-pTURP. A significant decrease in tPSA levels was observed after pTURP (p<0.05). Furthermore, the change in tPSA (delta tPSA) showed a linear and positive correlation with the weight of resected tissue.Conclusion: Palliative transurethral resection of the prostate in patients with advanced prostate cancer significantly reduces serum tPSA levels.
Elevation of Serum Total Prostate-Specific Antigen (PSA) Level as Predictor of Prostate Cancer (PCa) of Patient Following Transurethral Resection of Prostate (TURP) Sidiq, Muhammad; Utomo, Trisula; Kurniawan, Wikan
Contagion: Scientific Periodical Journal of Public Health and Coastal Health Vol 7, No 1 (2025): CONTAGION
Publisher : Universitas Islam Negeri Sumatera Utara, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30829/contagion.v7i1.23972

Abstract

Prostate cancer (PCa) is a significant global health issue, particularly in aging populations. In Indonesia, it is the fifth most common cancer. Diagnosis is often complicated by benign prostatic hyperplasia (BPH), which also elevates Prostate-Specific Antigen (PSA), limiting its specificity. This study aimed to establish an optimal preoperative PSA cutoff and assess the predictive utility of PSA, Neutrophil-Lymphocyte Ratio (NLR), and PSA Density (PSAD) for detecting PCa in patients undergoing Transurethral Resection of the Prostate (TURP). A retrospective cohort study analyzed 152 patients undergoing TURP at Gadjah Mada University Hospital (May 2018–July 2024) using a consecutive sampling method. Preoperative serum Total PSA, NLR, and PSAD were evaluated against postoperative histopathology. Bivariate and multivariate logistic regression were used to analyze relationships, while Receiver Operating Characteristic (ROC) curve analysis determined the optimal PSA cutoff. Prostate cancer was diagnosed in 19.1% of patients (n=29). ROC analysis identified a preoperative PSA cutoff of >19.95 ng/mL for predicting PCa, yielding an Area Under the Curve (AUC) of 0.863, with 75.9% sensitivity and 75.6% specificity. The multivariate analysis confirmed that elevated preoperative PSA (Odds Ratio [OR] 3.648), NLR (OR 3.868), and PSAD (OR 9.553) were all significant independent predictors of a PCa diagnosis. Among these, PSAD emerged as the strongest predictive marker. Preoperative serum PSA, NLR, and PSAD are valuable independent predictors for PCa in patients undergoing TURP for symptomatic BPH. A PSA cutoff of >19.95 ng/mL is a clinically relevant diagnostic threshold for this specific population. Employing a multi-marker panel, with particular emphasis on PSAD, can enhance risk stratification and help clinicians identify high-risk patients warranting further investigation for PCa when planning a TURP procedure.Keywords: Prostate Specific Antigen (PSA), Prostate Cancer (PCa), Benign Prostate Hyperplasia (BPH), Transurethral Resection of The Prostate (TURP)
Evaluation of Varicocelectomy Operative Therapy for Infertile Couples at the UGM Academic Hospital Sp.U, WIKAN KURNIAWAN
Academic Hospital Journal Vol 5, No 2 (2023)
Publisher : Rumah Sakit Akademik Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ahj.v5i2.86828

Abstract

Background: Infertility is a condition of the male or female reproductive system characterized by failure to achieve pregnancy after 12 months or more of having regular sexual intercourse without contraception. Since 2013,  Rumah Sakit Akademik UGM (RSA UGM) has providing varicocele therapy to infertile individuals. The Ivanissevich varicocelectomy procedure is used for varicocele therapy.Objective: This study intends to examine the management of varicocele patients at RSA UGM.Methods: This research is a retrospective study by opening medical records and interviews. The study population was all patients who underwent varicocelectomy surgery between 2013 and 2021. Data is presented in the form of  graphs.Results: The distribution of varicocele lateralization showed that out of 35 respondents, 23 respondents (66%) had one side varicoceles and 12 respondents (34%) both sides varicoceles. The distribution based on successful pregnancy shows that out of 35 respondents, 10 respondent couples (29%) have already gotten pregnant, 25 respondents (71%) haven't gotten pregnant. The distribution of varicocele lateralization in respondents who have children shows that 70% of respondents are one side and 30% of respondents are both sides. Complications of discomfort revealed that 88% of research participants had no complaints of postoperative pain, whereas 11% occasionally suffered pain following varicocele surgery.Conclusion: Varicocele that is one side is more common. Patients with one side varicocele who have surgery are more likely to become parents than those with both sides varicocele. At RSA UGM, the varicocelectomy success rate is comparable to the worldwide success rate.Keywords: Varicocele, success rate, one side, both sides.
The Effect of Bilateral Orchiectomy on Total Prostate Specific Antigen (TPSA) Levels in Prostate Adenocarcinoma Patients Sp.U, WIKAN KURNIAWAN
Academic Hospital Journal Vol 6, No 1 (2024)
Publisher : Rumah Sakit Akademik Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ahj.v6i1.98565

Abstract

AbstractBackground: Hormonal therapy is one treatment option for prostate cancer. There are two main categories of hormone therapy: surgical therapy and non-surgical therapy.  Orchiectomy is the surgical method of hormone therapy; medication supplementation is the non-surgical method. Many kinds of indicators are used to track the advancement of patients with prostate cancer receiving hormone therapy. tPSA levels are one of the markers that are regularly evaluated.Methods: In this retrospective study, PSA levels in patients with prostate adenocarcinoma cancer were evaluated before and after bilateral orchiectomy.  Use the search terms "prostate cancer" and "orchiectomy" to find research subject data in the UGM Academic Hospital's medical records installation between 2020 and 2023. The study's findings will be shown in a graphic and statistical analysis while protecting the subjects' anonymity.Results: Most of the participants (n=18, 60.0%) have pre-orchiectomy tPSA level of more than 30 ng/mL, while only almost a quarter (n=7, 23.3%) of participants have post-orchiectomy tPSA level of more than 30 ng/mL. The two research groups (p<0.0001) before and after the orchiectomy procedure, significantly differ between the two research groups based on Wilcoxon paired sample test analysis.Conclusion: TPSA levels are considerably decreased by bilateral orchiectomy.  
Co-Authors Hardi, Hidayu Permata Hariyanto, Satriawan Dini Muslim Mahardika Sidiq, Muhammad Trisula Utomo Utomo, Trisula