The evaluation of mobile application quality is essential in human–computer interaction studies, particularly in assessing usability and user experience (UX) which influence user satisfaction and continued usage. However, the usability level of Online Travel Agent (OTA) applications may vary, and empirical evaluations integrating multiple measurement methods remain limited, especially in regional contexts. This research is undertaken to analyze the usability and user experience of the Agoda application in South Sumatra using an integrated approach of the System Usability Scale (SUS) and User Experience Questionnaire (UEQ). A descriptive-evaluative quantitative approach was applied in this study. Research data were gathered by distributing an online questionnaire, resulting in 132 valid responses that were included in the analysis. The results show that the SUS score is 75, which falls into the good and acceptable category, indicating that the application is generally usable. Meanwhile, the UEQ results indicate that all dimensions have positive mean values ranging from 1.195 to 1.710, with most dimensions categorized as Good and one dimension categorized as Above Average. These findings indicate that the Agoda application provides a positive user experience in both pragmatic and hedonic aspects, supported by the SUS score of 75 and positive UEQ evaluations across all dimensions. However, improvements are still needed in certain dimensions, particularly perspicuity, to enhance clarity and ease of use. Overall, the integration of SUS and UEQ provides a comprehensive evaluation of usability and user experience, contributing to the improvement of OTA application quality.