Mustafidah -
Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

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TEST PHYTOCHEMICAL, TOXICITY AND ANTIBACTERIAL ACTIVITY FRACTION LEAF EXTRACT VARIOUS MAHANG (M acarang apruinosa (Miq.) Mull. Arg.) AGAINST Escherichia coli AND Staphylococcus aureus Mustafidah -; Chairul Saleh; Alimuddin -
PROSIDING SEMINAR KIMIA SEMINAR NASIONAL KIMIA 2014
Publisher : PROSIDING SEMINAR KIMIA

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Abstract

Phytochemical, to xicity and antibacterial act ivity tests of total extract, fractions of n-heksana, ethyl acetate and ethanol-water fro m mahang leaf (Macaranga pruinosa (M.) M. A.) fro m KRUS (Kebun Raya Unmul Samarinda), East Kalimantan has been carried out. Based on the secondary metabolites phytochemical test of the (Macaranga pruinosa (M.) M. A.) leaf show that total extract is contain alkaloid and steroid. n-hexane fraction is contain alkaloid and steroid. Ethyl acetate fract ion is contain steroid. Ethanol-water fract ion is contain alkaloid and phenolic. Brine shrimp lethality test values obtained Lethal Concentration 50 % (LC 50 ) total extract 27,5036 ppm , n-heksana fraction 12,0773 pp m, ethyl acetate fraction 23719,2305 ppm and ethanol-water fraction 250,0384 ppm. Antibacteria act ivity test of extracts for Staphylococcus aureus bacteria (positive Gram) and Escherichia coli (negative Gram) minimum inhibitor consentration of 0-1 % (b/v) fro m ext ract fractions of n-heksana and fractions ethyl acetate for Staphylococcus aureus bacteria and fractions ethyl acetate for Escherichia coli bacteria.
UJI FITOKIMIA, TOKSISITAS DAN AKTIVITAS ANTIBAKTERI dari EKSTRAK BERBAGAI FRAKSI DAUN MAHANG (Macarang apruinosa (Miq.) Mull. Arg.) terhadap BAKTERI Escherichia coli dan Staphylococcus aureus Mustafidah -; Chairul Saleh; Alimuddin -
JURNAL KIMIA MULAWARMAN Vol 12 No 2 (2015)
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

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Abstract

Phytochemical, toxicity and antibacterial activity tests of total extract, fractions of n-heksana, ethyl acetate and ethanol-water from mahang leaf (Macaranga pruinosa (M.) M. A.) from KRUS (Kebun Raya Unmul Samarinda), East Kalimantan has been carried out. Based on the secondary metabolites phytochemical test of the (Macaranga pruinosa (M.) M. A.) leaf show that total extract is contain alkaloid and steroid. n-hexane fraction is contain alkaloid and steroid. Ethyl acetate fraction is contain steroid. Ethanol-water fraction is contain alkaloid and phenolic. Brine shrimp lethality test values obtained Lethal Concentration 50 % (LC50) total extract 27,5036 ppm , n-heksana fraction 12,0773 ppm, ethyl acetate fraction 23719,2305 ppm and ethanol-water fraction 250,0384 ppm. Antibacteria activity test of extracts for Staphylococcus aureus bacteria (positive Gram) and Escherichia coli (negative Gram) minimum inhibitor consentration of 0-1 % (b/v) from extract fractions of n-heksana and fractions ethyl acetate for Staphylococcus aureus bacteria and fractions ethyl acetate for Escherichia coli bacteria.Keywords (Macaranga pruinosa (M.) M. A.), phytochemical test, Antibacteria activity test, LC 50 .