Wahyu Damayanti
Bagian Ilmu Kesehatan Anak Fakultas Kedokteran Universitas Gadjah Mada – RS DR Sardjito, Yogyakarta

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Improving Knowledge, Attitude, and Perception towards Childhood Diarrhea Using Interactive Discussion in Kulon Progo Community Jarir At Thobari; Wahyu Damayanti; Asal Wahyuni Erlin Mulyadi; Jonathan Hasian Haposan; Annisa Setiyaningrum; Shofya Indraguna; Sutarman S; Nailatul Arifah; Anggit Dewi Rahayu; Faridatun Khasanah; Al Razi Sena; Yati Soenaro
Jurnal Pengabdian kepada Masyarakat (Indonesian Journal of Community Engagement) Vol 7, No 2 (2021): June
Publisher : Direktorat Pengabdian kepada Masyarakat Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1231.509 KB) | DOI: 10.22146/jpkm.62861

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Introduction: Diarrhea is still a leading cause of death in the world in children, especially in children under 5 years. Diarrhea is a contagious disease with relatively high morbidity and mortality rates. Rotavirus is a cause of diarrhea in children and is a very important public health problem in both developed and developing countries. Parents' knowledge is one of the causes of diarrhea due to parents' ignorance of the causes of diarrhea, how diarrhea is transmitted and how to prevent diarrhea.Methods: This explanatory mixed qantitative-qualitative method with a quasi experimental design study to determine the effect of interactive discussion on changes in knowledge, attitudes, and perceptions towards the prevention and management of childhood diarrhea among mothers and children living in the area of The Ash-Shiddiqiyah Orphanage located in Central Sremo, Hargowilis, Kokap, Kulon Progo Regency, Yogyakarta.Results: The activities were conducted on November 29th, 2020 with 67 participants consisting of 54 children and 13 mothers from the area. The questionnaire results showed that the posttest scores in all sections (knowledge, attitudes, and perceptions) were significantly higher compared to the the pretest scores. There were increment of 1.33 points in knowledge (p<0.001), 0.5 points in attitudes (p<0.001),  0.4 points in perception (p<0.05), and 0.76 points in overall scores (p<0.001). Interviewees agreed that the intervention has been properly conducted with clear delivery, easy to understand for both adults and children, and ability to two-way communication. Technology utilization might help the understanding of the audience. Besides, a small group discussion in the session may benefit the participants to ask more confidently compared to asking in the middle of large group due to shame.Conclusion: Interactive discussion could be used to improve knowledge, atittude and perception towards childhood diarrhea. The delivery of interactive discussion using simple language for targetted population, adoption of small group discussion and technology utilization might help the effectiveness of the intervention. Further study is needed to identify effective ways to promote the childhood diarrhea management and prevention in community.
Prevalensi Gangguan Elektrolit Serum pada Pasien Diare dengan Dehidrasi Usia Kurang dari 5 Tahun di RSUP Dr. Sardjito Tahun 2013-2016 Rosyida Avicennianing Tyas; Wahyu Damayanti; Eggi Arguni
Sari Pediatri Vol 20, No 1 (2018)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (492.276 KB) | DOI: 10.14238/sp20.1.2018.37-42

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Latar belakang. Hingga saat ini, diare masih menjadi salah satu masalah kesehatan dunia, terutama di negara berkembang, termasuk di Indonesia. Salah satu komplikasi lanjutan dari dehidrasi pada diare adalah gangguan elektrolit serum. Tujuan. Untuk mengetahui prevalensi gangguan elektrolit serum pada pasien diare dengan dehidrasi serta karakteristik klinis pasien dan hubungan antara derajat dehidrasi terhadap gangguan elektrolit serum.Metode. Penelitian retrospektif dengan rancangan cross sectional menggunakan data rekam medis. Perbedaan dianalisis menggunakan uji Chi-square.Hasil. Jumlah pasien yang memenuhi kriteria adalah 173 pasien, 115 pasien yang memiliki data rekam medis lengkap. Tujuh puluh di antaranya mengalami gangguan elektrolit serum. Jenis gangguan elektrolit serum terbanyak dialami adalah hipokalsemia (17,34%). Dari 173 pasien diare dengan dehidrasi, 64,74% berjenis kelamin laki-laki, 43,35% berusia 12-35 bulan, 83,24% mengalami muntah, 52,6% mengalami demam, 4,62% mengalami dehidrasi berat. Penelitian ini tidak membuktikan adanya hubungan signifikan antara derajat dehidrasi terhadap gangguan elektrolit (p=0,243).Kesimpulan. Prevalensi gangguan elektrolit serum pada pasien diare dengan dehidrasi pada anak adalah 40,46%.
Perbandingan Tatalaksana Konstipasi Kronis antara Disimpaksi per Oral dengan per Rektal di Instalasi Kesehatan Anak RS DR Sardjito Yogyakarta Wahyu Damayanti; Pradini Pradini; Zamrina Zamrina; M. Juffrie
Sari Pediatri Vol 14, No 4 (2012)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp14.4.2012.224-9

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Latar belakang. Konstipasi adalah kelainan yang sering terjadi dan menimbulkan masalah yang serius padabayi dan anak. Penyebab konstipasi dapat dibagi menjadi penyebab non organik/fungsional dan penyebaborganik. Tatalaksana anak dengan konstipasi fungsional meliputi beberapa langkah, 1) edukasi, 2) pengeluaranfeses/disimpaksi, 3) fase pemeliharaan. Pada disimpaksi dan fase pemeliharaan diperlukan laksansia secara oralataupun rektal.Tujuan. Membandingkan disimpaksi oral (Laktulose) dengan per rektal (phosphate enema) pada anakdengan konstipasi kronis, kedua obat ini dari golongan yang sama yaitu laksansia osmotikMetode. Merupakan penelitian uji klinis acak terkendali. Sampel penelitian adalah anak konstipasi fungsional yangberobat jalan dan dirawat di Instalasi Kesehatan Anak RS Dr. Sardjito Yogyakarta dan memenuhi kriteria inklusidan kriteria eksklusi, usia antara 􀁴6 bulan – 14 tahun akan dilakukan uji disimpaksi per oral atau per rektal.Hasil. Angka kesembuhan pada kelompok terapi per oral lebih sedikit dibanding per rektal (=0,636, IK95% 0, 336-1,205), p=0,162. Efek samping yang timbul yaitu kembung (RR=0,857, IK 95% 0,633-1,160),p=0,285, nyeri perut (RR=0,583, IK 95% 0,141-2,410), p=0,312, diare (RR=0,952, IK 95% 0,611-1,484),p=0,832. Penerimaan terhadap obat yang diberikan pada anak (RR=1,000, IK 95% 0,699-1,448), p=1,000,pada orang tua (RR=1,1670, IK 95% 0,862-1,579), p=0,317. Perubahan gejala konstipasi setelah intervensiobat, yaitu retensi (RR=1,40, IK 95% 0,112-17,543), p=0,802, soiling (RR=1,40, IK 95% 0,875-2,237),p=0,171, konsistensi feses (RR=1,20, IK 95% 0,839 -1,716), p=0,071.Kesimpulan. Tidak terdapat perbedaan efektifitas pada kedua kelompok, hanya dalam lama terapi lebihcepat pada laksansia per rektal dibandingkan per oral. Tidak terdapat perbedaan yang bermakna pada keduakelompok dalam mengurangi retensi, nyeri saat defekasi dan konsistensi feses. Tidak ditemukan efek sampingyang bermakna pada pemakaian laksansia per oral ini. Laksansia per oral lebih mudah diberikan dibandinglaksansia per rektal walau hasil tidak berbeda bermakna.
The role of exclusive breastfeeding in prevention of childhood epilepsy Alexander Kurniadi; Elisabeth Siti Herini; Wahyu Damayanti
Paediatrica Indonesiana Vol 55 No 5 (2015): September 2015
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (92.651 KB) | DOI: 10.14238/pi55.5.2015.282-6

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Background Epilepsy affects 1% of children worldwide. The highest incidence is in the first year of life, and perinatal factors, such as hypoxic-ischemic injury, infection, and cortical malformation may play etiologic roles. Breast milk contains optimal nutrients for human brain in early life. Breastfeeding has been associated with lower risk of infections, better cognitive and psychomotor development. However, the role of breastfeeding in preventing childhood epilepsy remains unclear. Objective To evaluate an association between exclusive breastfeeding and childhood epilepsy. Methods A case-control study conducted from 1 May to 3 July 2013 involving children with epilepsy aged 6 months to 18 years who were attending pediatric outpatient clinic of Dr. Sardjito Hospital, Yogyakarta. Neurologically normal children, individually matched by age and sex, visiting the same clinic were considered as controls. Exclusion criteria were children with structural brain abnormality, history of epilepsy in family, and who had history of neonatal seizure, intracranial infection, febrile seizure, and head trauma before onset of epilepsy. History of breastfeeding was obtained by interviewing the parents. The difference of exclusively breastfeeding proportion between cases and controls was analyzed by McNemar test. Results The total number of participants was 68 cases and controls each. Subjects with epilepsy had lower proportion of exclusively breastfed (48.5%) compared with controls (54.4%), but the difference was not statistically significant (P=0.541). Exclusively breastfeeding showed no statistical significance in decreasing risk of epilepsy (OR=0.71; 95%CI 0.32 to 1.61). Conclusions Exclusive breastfeeding for 4-6 months has no effect against childhood epilepsy.
Effect of adding tyndallized probiotics to the World Health Organization standard therapy for acute diarrhea in children Kesatrianita Mawarni Fanny; Wahyu Damayanti; Mohammad Juffrie
Paediatrica Indonesiana Vol 52 No 2 (2012): March 2012
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (95.576 KB) | DOI: 10.14238/pi52.2.2012.91-94

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Background Diarrhea is the major cause of morbidity and mortalityin children. Probiotics can decrease the frequency and durationof diarrhea. There are two types of probiotics, live and tyndallized.Tyndallized probiotics have been stetilized, so they are unable to produceactive metabolites, but may have an effect on human immunity.Objective To evaluate the effectiveness of supplementing WHOstandard therapy with tyndallized probiotics in children withacute, watery diarrhea.Methods We performed a randomized, single-blind, controlledtrial in children aged 3-60 months who were diagnosed with acute,watery diarrhea at Gunungsitoh General Hospital, Nias, NorthSumatera. Subjects were collected by consecutive sampling byway of parent interviews.Results One hundred subjects with acute, watery diarrhea weredivided into 2 groups of 50. One group was treated with onlyWHO standard therapy for acute, watery diarrhea. The othergroup was treated by WHO standard therapy with the additionof tyndallized probiotics. There were no significant differences inbasic characteristics between the two groups. Diarrheal durationfor the group receiving WHO standard therapy only was 3.95 ±1.3 days, while that of the group receiving both WHO standardtherapy and tyndallized probiotics was 4.6 ± 2.3 days (P > 0.05).Diarrheal frequency on the fifth day in the WHO standard therapygroup was 1.90 ± 0.99 times per day, while that of the tyndalhzedprobiotic group was 1.56 ± 0.67 times per day (P > 0.05).Conclusion There were no significant differences between WHOstandard therapy alone and WHO standard therapy with the additionof tyndallized probiotics for decreasing the duration and frequency ofdiarrhea in children. [Paediatr lndones. 2012;52:91-4].
Efficacy of synbiotic and probiotic treatments on acute watery diarrhea in children Ani Isti Rokhmawati; Wahyu Damayanti; Madarina Julia
Paediatrica Indonesiana Vol 52 No 4 (2012): July 2012
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (106.439 KB) | DOI: 10.14238/pi52.4.2012.209-12

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Background In developing countries, acute watery diarrhea isa common cause of morbidity and mortality in children. Givingsynbiotics or probiotics may decrease the severity of diarrhea.Objective To compare the efficacy of synbiotics and probioticsin decreasing the frequency of diarrhea, shortening the duration,and increasing patient body weight.Methods This was a double􀀷blind, randomized clinical trial tocompare the effects of synbiotic vs probiotic treatment in childrenaged 6􀀷59 months v.ith acute watery diarrhea. This study wasperformed from October to December 2010 in two hospitals inCentral Java. Subjects received either synbiotics or probioticstv.ice daily for five days. The measured outcomes were durationof diarrhea, daily frequency of diarrhea, and increase in bodyweight.Results There was no significant difference in the mean durationof the diarrhea in the synbiotic and probiotic groups, 3.92 days(SD 0.79) vs 3.80 days (SD 0.82) ,(P􀀸0.35), respectively. Nor didwe observe a significant difference in the mean increase in bodyweight in the synbiotic and probiotic groups, 150 g (SD 49.7) vs160 g (SD 48.9), (P􀀸 0.67), respectively.Conclusion We observed no significant differences in efficacy ofsynbiotic and probiotic treatment for management of acute waterydiarrhea. [Paediatr Indones. 2012;52:209,12].
Impact of malnutrition on febrile neutropenia in children with acute lymphoblastic leukemia during induction phase chemotherapy Marshalla Agnes; Pudjo Hagung Widjajanto; Wahyu Damayanti
Paediatrica Indonesiana Vol 58 No 6 (2018): November 2018
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (257.704 KB) | DOI: 10.14238/pi58.6.2018.298-304

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Background Acute lymphoblastic leukemia (ALL) is the most common malignancy in children and adolescents. Febrile Neutropenia (FN) is a medical emergency on ALL that often leads to death. Nutrition status assessment on ALL patient is important because malnutrition can reduce the tolerance of chemotherapy, increase incidence of infection and decrease survival rate. Objectives To assess malnutrition as a risk factor for FN in children with ALL. Methods This case-control study was performed at Sardjito Hospital, Yogyakarta on patients aged 1 month to 18 years diagnosed with ALL and undergoing induction phase chemotherapy between January 2013 and December 2015. The case and control subjects were children with and without FN, respectively. Febrile neutropenia was confirmed by patients temperature above 38ºC at one measurement and a peripheral neutrophil count of less than 1,000/mm3. Malnutrition was defined as body weight-for-height was between -2 and <-3 standard deviation. Subjects were included using simple random sampling. Result Bivariate analysis showed a significant correlation between malnutrition and FN (OR 2.62; 95%CI 1.07 to 6.45; P=0.03). However, there was no inverse correlation between socioeconomic status and FN (OR 1.1; 95%CI 0.42 to 2.41; P=0.83). There was no correlation between nutritional status and duration of FN (P= 0.48). Conclusion Malnutrition is a risk factor for FN in children with acute lymphoblastic leukemia.
Influence of initial treatment delay on overall survival and event-free survival in childhood acute lymphoblastic leukemia Irenne Purnama; Pudjo Hagung Widjajanto; Wahyu Damayanti
Paediatrica Indonesiana Vol 61 No 4 (2021): July 2021
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi61.4.2021.217-22

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Background Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy. Initial treatment delay is a modifiable prognostic factor that significantly affects overall survival (OS) and event-free survival (EFS) of childhood ALL in high-income countries. Nevertheless, the effect of delayed initial treatment in low-middle income countries had not been determined. Objective To analyze relationships between initial treatment delay with overall survival and event-free survival in children with ALL. Methods A retrospective study was conducted in children aged < 18 years newly diagnosed with ALL L1 and L2 from January 2013 until December 2018 at Dr. Sardjito Hospital, Yogyakarta. Initial treatment delay was defined as a time interval of more than 3 days between diagnosis and treatment. The outcomes of the study were OS and EFS. Negative events were defined as remission failure, relapse, dropping out, and death. Overall survival (OS) and event free survival (EFS) were analyzed by Kaplan-Meier and log-rank tests. Results Of 341 subjects, 188 (55.5%) underwent delayed initial treatment. There were no significant relationships between initial treatment delay and OS (HR 0.845; 95%CI 0.548 to 1.302; P=0.445) or EFS (HR=0.937; 95%CI 0.689 to 1.275; P=0.971). Multivariate analysis revealed that age was an independent prognostic factor for both OS (P<0.001) and EFS (P<0.001). Conclusion Initial treatment delay is not associated with OS or EFS. Age is an independent predictor for both OS and EFS.
Prevalensi Infeksi Helicobacter pylori pada Anak dengan Gejala Gastrointestinal di Rumah Sakit Umum Pusat Dr. Sardjito Yogyakarta R Yuli Kristyanto; Titis Widowati; Wahyu Damayanti
Sari Pediatri Vol 24, No 2 (2022)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp24.2.2022.106-11

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Latar belakang. Prevalensi infeksi Helicobacter pylori (H. pylori) di berbagai wilayah bervariasi. Infeksi H. pylori pada anak umumnya tidak menunjukkan gejala khas, tetapi dapat mengakibatkan berbagai komplikasi. Tujuan. Melihat prevalensi dan gejala infeksi H. pylori pada anak dengan gejala gastrointestinal di Yogyakarta.Metode. Data dikumpulkan dari pasien anak dengan keluhan dispepsia, nyeri perut berulang, muntah berulang, dan buang air besar disertai darah yang dicurigai mengalami infeksi H. pylori di RSUP. Dr. Sardjito, Yogyakarta. Diagnosis infeksi H. pylori ditegakkan dengan pemeriksaan endoskopi dan histologi.Hasil. Didapatkan 138 subyek yang memenuhi kriteria kemungkinan terinfeksi oleh kuman H. pylori didapatkan pada 16,7% (23/138) pasien anak. Prevalensi infeksi menurut usia pada 3-5 tahun sebesar 14,3% (3/21), usia 6-11 tahun sebesar 16,7% (10/60), dan usia 12-18 tahun sebesar 17,5% (10/57). Tidak ada hubungan bermakna antara infeksi H. pylori dengan gejala spesifik tertentu.Kesimpulan. Prevalensi infeksi H. pylori pada anak yang bergejala klinis di Yogyakarta, Indonesia lebih rendah daripada dari wilayah lain di dunia.