S. Wahyuono
Faculty of Pharmacy, Gadjah Mada University, Yogyakarta Indonesia

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Journal : INDONESIAN JOURNAL OF PHARMACY

Identification of cubebin and epicubebin isolated from Piper cubeba L.f fruits with two D-NMR spectroscopy Wahyono .; S. Wahyuono; A. Mursyidi; H. Timmerman; R. Verpoorte; L. Hakim
Indonesian Journal of Pharmacy Vol 16 No 4, 2005
Publisher : Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (406.682 KB) | DOI: 10.14499/indonesianjpharm0iss0pp232-238

Abstract

One of the isolated active compound of the tracheospasmolytic from kemukus fruits (Piper cubeba L.f) is cubebin. The problem occurred when cubebin (C20H20O6) mixed with its epimer because of the difficultly to identify the structure by 1D-NMR spectroscopy. Structure identification then was conducted by 2D-NMR spectroscopy, so the structure of cubebin and epicubebin can be clear identified. Key words : Cubebin, epicubebin, identification, 2D-NMR