INDONESIAN JOURNAL OF PHARMACY
Vol 16 No 4, 2005

Identification of cubebin and epicubebin isolated from Piper cubeba L.f fruits with two D-NMR spectroscopy

Wahyono . (Faculty of Pharmacy, Gadjah Mada University, Yogyakarta Indonesia)
S. Wahyuono (Faculty of Pharmacy, Gadjah Mada University, Yogyakarta Indonesia)
A. Mursyidi (Faculty of Pharmacy, Gadjah Mada University, Yogyakarta Indonesia)
H. Timmerman (Division of Medicinal Chemistry, Department of Pharmacochemistry, VrijeUniversiteit, The Netherlands)
R. Verpoorte (Department of Pharmacognosy, Gorleaus Laboratory, Leiden University, The Netherlands)
L. Hakim (Faculty of Pharmacy, Gadjah Mada University, Yogyakarta Indonesia)

Article Info

Publish Date
01 Oct 2005

Abstract

One of the isolated active compound of the tracheospasmolytic from kemukus fruits (Piper cubeba L.f) is cubebin. The problem occurred when cubebin (C20H20O6) mixed with its epimer because of the difficultly to identify the structure by 1D-NMR spectroscopy. Structure identification then was conducted by 2D-NMR spectroscopy, so the structure of cubebin and epicubebin can be clear identified. Key words : Cubebin, epicubebin, identification, 2D-NMR

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Journal Info
INDONESIAN JOURNAL OF PHARMACY
Website

Abbrev

3

Publisher

Universitas Gadjah Mada

Subject

Medicine & Pharmacology

Description

Indonesian Journal of Pharmacy (ISSN-e: 2338-9486, ISSN-p: 2338-9427), formerly Majalah Farmasi Indonesia (ISSN: 0126-1037). The journal had been established in 1972, and online publication was begun in 2008. Since 2012, the journal has been published in English by Faculty of Pharmacy Universitas ...