Andreanus A Soemardji
Department of Pharmacy, Bandung Institute of Technology, Bandung, Indonesia.

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Analysis of nicotine in various organs of male mice after inhalation of cigarette smoke Irda Fidrianny; IGNA Supradja; Andreanus A Soemardji
Indonesian Journal of Pharmacy Vol 15 No 4, 2004
Publisher : Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (179.457 KB) | DOI: 10.14499/indonesianjpharm0iss0pp207-210

Abstract

Nicotine is one of dangerous components in cigarette smoke, there for concentration of nicotin in organ quantitative in organs must be determined. Qualitative and quantitative thin layer chormatographic analysis of nicotine in various organs of male mice after inhalation of cigarette smoke has been carried out. Nicotine was extracted with chloroform in ammoniacal medium and determined by spectrophotodensitometry. The nicotine content in lung is higher than kidney and liver.Key words: nicotine, lung, kidney, liver, male mice