Article Per Year (5 Year)
p-Index From 2021 - 2026
0
P-Index
This Author published in this journals
All Journal Jurnal Kimia Mulawarman
Siti Hadijah
Jurusan Kimia, Fakultas MIPA, Universitas Syiah Kuala, Banda Aceh
Chemistry

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Isolation Of Antioxidant Compounds Of N-Hexane Extract Of Nutmeg (Myristica Fragrans Houtt) Leaves Binawati Ginting; Siti Hadijah; Hira Helwati
JURNAL KIMIA MULAWARMAN Vol 15 No 1 (2017)
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30872/jkm.v15i1.584

Abstract

The isolation of antioxidant active compounds from n-hexane extract of nutmeg leaves (Myristica fragrans Houtt) with dipphenylpicrylhydrazyl (DPPH) has been carried out. n-Hexane extract of nutmeg leaves (0.35%) was obtained by partitioning of methanol extract (535.7 g) using n-hexane solvent. Isolation of active compound of n-hexane extract with gravitational column chromatography gradient elution of n-hexane : ethyl acetate with ratio (9 : 1) – (7 : 3) obtained 7 mixed fraction of MFHD1 - MFHD 7. MFHD 2 fraction further isolated obtained MFHD 2.1. The nutmeg n-hexane extracts and their fractions showed strong antioxidant activity with IC50 values ​​<100 ppm except MFHD 6 fraction showed for IC50 values of 114.95 ppm. The most potent antioxidant activity in MFHD 4 fraction with IC50 value of 0.729 ppm (compared with vitamin C value of IC50 7,875 ppm as positive control). The GC-MS analysis of the MFHA 2.1 fraction shows the presence of sitostenone and eucalyptol compounds, both of which have been reported to have been isolated from several different plants and have antioxidant activity.
Co-Authors Binawati Ginting Hira Helwati