Achmad Zulfa Juniarto
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HISTOPATOLOGI SPERMATOGENESIS TESTIS TIKUS WISTAR DIABETES MELITUS Siera Adelati; Achmad Zulfa Juniarto; Ika Pawitra Miranti
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 5, No 4 (2016): JURNAL KEDOKTERAN DIPONEGORO
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (987.966 KB) | DOI: 10.14710/dmj.v5i4.15962

Abstract

Latar Belakang: Pada penderita diabetes melitus tingginya kadar gula darah dapat meningkatkan ROS sehingga mengakibatkan stres oksidatif. Stres oksidatif di dalam sel dapat mengganggu proses respirasi sel sehingga menyebabkan hilangnya fungsi potensial membran mitokondria dan memicu terjadinya apoptosis sel. Stres oksidatif pada testis dapat mengganggu tahapan proses spermatogenesis pada tubulus seminiferus.Tujuan: Membuktikan adanya gangguan yang bermakna terhadap tahapan spermatogenesis pada tikus Wistar jantan dengan diabetes melitus dibandingkan tikus normal.Metode: Penelitian ini menggunakan desain true experimental dengan post test only control group. Sampel sebanyak 32 tikus Wistar dibagi menjadi 2 kelompok. Kelompok kontrol (K) hanya diberi pakan standar dan kelompok perlakuan (P) dibuat kondisi diabetes melitus dengan diinduksi aloksan 150mg/kgBB 1 kali pada hari ke 8. Masing – masing kelompok diukur kadar gula darah pada hari ke 8, 14, dan 28. Setelah 21 hari tikus diterminasi. Testis diambil untuk dilakukan pengamatan histopatologi dengan pengecatan HE dan dinilai menurut kriteria skor Johnsen.Hasil: Didapatkan nilai median kelompok perlakuan adalah 8.6 (range 6 – 9.2), kelompok kontrol yaitu 10 (range 7 – 10). Berdasarkan analisis analitik uji normalitas data uji Saphiro-Wilk didapatkan hasil yang tidak normal p<0.001. Hasil uji beda non-parametrik Mann Whitney didapatkan hasil yang signifikan antara kelompok kontrol dan perlakuan yaitu p=0.00011.Kesimpulan: Kadar gula darah yang tinggi pada kondisi diabetes melitus dapat mengganggu tahapan spermatogenesis.
Life Quality Of End Of Life Patient's Family in Intensive Care Units Noor Fitriyani; Reni Sulung Utami; Achmad Zulfa Juniarto
JNKI (Jurnal Ners dan Kebidanan Indonesia) (Indonesian Journal of Nursing and Midwifery) Vol 6, No 1 (2018): MARET 2018
Publisher : Alma Ata University Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (87.416 KB) | DOI: 10.21927/jnki.2018.6(1).16-24

Abstract

Fifty percent of end-of-life patients spend the last time of their life in the Intensive Care Unit (ICU). End of life conditions have an impact on the psychological, physical, social, and family environment that affect the quality of life of other families. Family welfare will have an impact on care outcomes, hospitalization time, and patient stressor levels. The purpose of this study was to explore the life quality of end of life patient's family in ICU. This research used qualitative method with descriptive phenomenology approach. Sampling was done by purposive sampling technique with 9 participants. data were collected through in-depth interviews and analyzed using the Colaizzi method.  The data validity was designed to meet the principle of triangulation of researchers and theory. The results showed 7 dimensions of life quality of end of life patient's family of physical health (fatigue, sleep disorder, headache, decreased appetite), mental health (anxiety, sadness, hope of improved family health condition), spiritual health (acceptance), health social (social support), daily life (daily life adjustment), financial health (financial burden), and environment (opportunity to get information, family infrastructure).  This study concludes that end of life condition of critical patients impacts on the 7 dimensions of family life quality. Nurses should pay attention to the family life quality because it affected the condition of the patient  and family as the care service unit. Keywords: Life Quality, Family, End Of Life, Intensive Care Unit 
The Description Of Diabetics’ Acceptance Stage Toward Diabetes Mellitus’ Diagnoses Ana Nistiandani; Achmad Zulfa Juniarto; Niken Safitri Dyan
JNKI (Jurnal Ners dan Kebidanan Indonesia) (Indonesian Journal of Nursing and Midwifery) Vol 6, No 1 (2018): MARET 2018
Publisher : Alma Ata University Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (92.303 KB) | DOI: 10.21927/jnki.2018.6(1).25-31

Abstract

Abstract Diabetes Mellitus (DM) is a chronic condition which requires various kinds of lifetime treatment which cause grief. Grief has stages which can be passed though normally with the attainment of acceptance stage. Acceptance attainment renders a description maintaining that grief in its process is undergone normally through uncomplicated grief reaction and emotional responsiveness. A diabetics who manages to attain the acceptance stage will have a better glycemic control, while a diabetics with a low acceptance stage may experience an ineffective coping, improper self-treatment, and distress increase, all of which end up in a bad glycemic control which causes physical complications. This suggests that a description of s’ acceptance stage is important to identify. Accordingly, the aim of this research is to identify and analyze the description of diabetics’ acceptance of DM diagnoses. The method utilized is descriptive-observational, the data collected using the ‘Acceptance of Disease and Impairments Questionnaire’ (ADIQ). The analysis employed in this research is a descriptive analysis. The sampling technique used is consecutive sampling. The research result shows that, based on the diagram of ADIQ administered on 20 s, there are 30% found to be in the stage of acceptance, while there exist 70% to be in the stage of not yet attaining acceptance, which comprises denial (20%), resistance (10%), and sorrow (40%). Failure in attaining the acceptance stage is caused by the s’ still being in the states of denial, resistance, and sorrow. Based on the research result, it can be concluded that the s dominantly stay at the stage of not yet attaining acceptance. The diabetics who have attained acceptance may still be exposed to the risk of undergoing a maladaptive response which may trigger depression, anxiety, worsened physical health, self-treatment discontinuation, powerlessness, low self-esteem, social isolation, even suicidal drive. This is all caused by grief which constitutes a fluctuate condition where every diabetes can contribute to describing his or her condition at every stage. Keywords: stages of grief, acceptance, denial, resistance, sorrow