Benyamin Makes
Department of Anatomic Pathology, Faculty of Medicine Universitas Indonesia/Cipto Mangunkusumo Hospital, Jakarta.

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Journal : Medical Journal of Indonesia

Diagnostic accuracy of frozen section in various thyroid disorders as compared with paraffin section from the same cases Kuntjoro, Kuntjoro; Makes, Benyamin
Medical Journal of Indonesia Vol 4, No 1 (1995): January-March
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (535.716 KB) | DOI: 10.13181/mji.v4i1.906

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Accuracy of frozen-section combined with imprint and fine needle aspiration biopsy in thyroid nodules Makes, Benyamin
Medical Journal of Indonesia Vol 16, No 2 (2007): April-June
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (114.544 KB) | DOI: 10.13181/mji.v16i2.257

Abstract

Thyroid malignancy can be found on 5% of thyroid nodules. In order to better managed of thyroid nodules, skills to differentiate benign from malignant cases were needed. Fine needle aspiration biopsy (FNAB) was done preoperatively while frozen section (FS) and imprint cytology (IC) should be done intra-operatively. The objective of this research paper is to evaluate the diagnostic accuracy of FNAB versus frozen section combined with imprint cytology (FS+IC) in thyroid nodules at the Anatomic-Pathology Department FMUI-CM Hospital, Jakarta. This diagnostic test, used data from clinico-pathological records in Anatomic Pathology Department, Faculty of Medicine University of Indonesia / Dr.Cipto Mangunkusumo General Hospital, Jakarta, Indonesia during 1999-2003. Specimens with complete data of FNAB results, data of FS and slides of IC. All formalin fixed`specimens were reevaluated and used as the golden standard. Sensitivity, spesificity and accuracy of FS+IC were higher than FNAB (86.8% vs 73.7% ; 99.0% vs 83.9% ; 94.8% vs 80.5% respectively). If the results of FNAB were concordant with the result of FS+IC, the combined examination yields accuracy of 95.1%. The evaluation of frozen section combined with imprint cytology is very useful, because this examination significantly showed high accuracy in diagnosing thyroid malignancy. (Med J Indones 2007; 16:89-93)Keywords: thyroid nodules, FNAB, frozen section, imprint cytology, accuracy
Parathyroid carcinoma: review of a problematic case Putri, Rizky I.; Makes, Benyamin
Medical Journal of Indonesia Vol 21, No 3 (2012): August
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (701.077 KB) | DOI: 10.13181/mji.v21i3.496

Abstract

Parathyroid carcinoma (PTCA) is a rare neoplasm that accounts for less than 1% of primary hyperparathyroidism cases. Several clinical and biochemical features can directing to PTCA, but accurate pre and intraoperative diagnosis are still difficult. This study presents a case of PTCA that diagnosed postoperatively with a discussion of microscopic feature. The surgical exploration revealed an enlarged parathyroid mass which invade recurrent laryngeal nerve and right thyroid gland. Histologic features showed tumor nodules separated by thick fibrous band with capsular invasion and local infiltration to adjacent tissues. The final diagnosis of PTCA was made based on clinical feature and specimens examination. (Med J Indones. 2012;21:170-4)Keywords: Diagnosis, invasion, parathyroid carcinoma, primary hyperparathyroidism