Gani Gunawan
Kedokteran Nuklir, Instalasi Radiologi, RSUP Dr. Kariadi Semarang

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search
Journal : YOUNGSTER PHYSICS JOURNAL

Analisis tingkat kontaminasi permukaan daerah kerja dan laju paparan radiasi pada Instalasi Kedokteran Nuklir Ukhti Lailun Nisa; Gani Gunawan; Zaenal Arifin; Eko Hidayanto
Youngster Physics Journal Vol 6, No 1 (2017): Youngster Physics Journal Januari 2017
Publisher : Jurusan Fisika, Fakultas Sains dan Matematika, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (643.313 KB)

Abstract

The surface contamination of the work area and the rate of radiation exposure at nuclear medicine installation have an effect to the safety workers and the society directly or indirectly. This study aims to analyze the level of surface contamination and the rate of radiation exposure on the nuclear medicine installation and to identify the activity of half time 99mTc and 131I. The used method is measuring the surface contamination of the work area caused by the use of radiopharmaceutical through the distance between the detector window and the 3 cm measured region. Meanwhile, the rate of radiation exposures is used to measure the sides of each room with a distance 1 meter in the area control and to measure the activity of radioisotope that is monitored once every an hour for 6.03 hours to 99mTc and every day for 8 days to 131I of the initial measurement and compares with the result calculation. The measurement result of the level of the surface contamination in various areas of all rooms is 0.000-5.272 Bq/cm2 and it is classified into low to medium level of contamination. The measurement result of the rate of radiation exposure in the control area is 0.022-1.404 µSv/h which is still classified under 10 µSv/h. So, it can be concluded that it is safe for workers and other patients. The use of radioisotope on the nuclear medicine installation in accordance with their needs and always consider to the principles of the radiation protection, therefore the level of contamination and the rate of radiation exposure is low. The result of the measurement and the calculation of the activity of 99mTc are decays into a half after 6.03 hours and the activity of 131I is decays a half after 8 days. Keywords: Radiation Protection, Contamination, The rate of Radiation Exposure Half Time Activity.
Biodistribusi radiofarmaka Tc99m DTPA pada pemeriksaan renografi Dini Desita; Wahyu Setia Budi; Gani Gunawan
Youngster Physics Journal Vol 6, No 2 (2017): Youngster Physics Journal April 2017
Publisher : Jurusan Fisika, Fakultas Sains dan Matematika, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (634.488 KB)

Abstract

Reasearch about biodistribution on 25 patients with renography examination using the technique of in-vivo and in-vitro in nuclear medicine has conducted. The purpose of this reasearch is to determinate the value of activity on examination of kidney and bladder, determine biodistribution Tc99m DTPA on examination of the kidney and bladder, futhermore to determine biological half-life time in the kidney. Reasearch carried out by using radioisotope Tc99m with DTPA which carrier substances for examination of the kidney. Renography examination is done by injecting Tc99m DTPA intravenously into the patient’s arm as much as 4 to 8 mCi conjuction with posterior imaging in the kidney area in 10 to 15 minutes by using a gamma camera. Based on percentage of activity in getting from both kidneys, the left kidney is higher in compared to the right kidney. As for the bladder in second patients increased very significant due to illness in patients with chronic renal failure so that the kidney function is not functioning properly and radiopharmaceutical absorbed more in the bladder. The results of biodistribution activity Tc99m DTPA percentage is high on the bladder. The results obtained from the average half-life time (0,235 ± 0,001) hours. While the results of Tc99m DTPA effective half-life time in the body of each patient in the range of 0,5 to 2 hours. First patients has a longest biological half-life time. Differences in the effective half-life time of each patient is affected by the elimination of biological or biological half-life time of each patient is different too.Keywords: Tc99m, DTPA, renography, biodistribution, effective half-life time.