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All Journal Majalah Kedokteran Bandung Damianus Journal of Medicine Jurnal Pengabdian Kepada Masyarakat (Indonesian Journal of Community Engagement) Jurnal Medika Hutama Cermin Dunia Kedokteran Cermin Dunia Kedokteran
Angela Shinta Dewi Amita
Departemen Ilmu Kesehatan Mata, FKIK, Universitas Katolik Indonesia Atma Jaya
Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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Retinopati Klorokuin dan Hidroksiklorokuin Ivana Beatrice Alberta; Maria Vania Tri Ekaputri; Angela Shinta Dewi Amita
Cermin Dunia Kedokteran Vol 47 No 8 (2020): Oftalmologi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v47i8.591

Abstract

Klorokuin dan hidroksiklorokuin kerap digunakan sebagai tatalaksana berbagai penyakit autoimun, infeksi malaria, dan kini menjadi salah satu obat penanggulangan darurat Coronavirus Disease-19 (COVID-19). Kedua obat ini berpotensi sebagai antiinflamasi dan antivirus. Namun penggunaannya sering menimbulkan berbagai efek samping seperti pada jantung, saraf, saluran pencernaan, dan mata. Efek samping pada mata dapat berupa toksisitas retina yang dapat berakhir menjadi retinopati ireversibel. Guna menghindari cacat permanen, diperlukan pencegahan yang tepat dengan mengenali faktor risiko dan skrining, serta pemantauan ketat penggunaan obat. Chloroquine and hydroxychloroquine are often used as a treatment for autoimmune disease, malaria infection, and now become an emergency drug for Coronavirus Disease-19 (COVID-19). Both are potential anti-inflammatory and antiviral agents. However, potential various side effects to the heart, nerves, gastrointestinal tract, and also eyes must be considered. Side effects on the eyes are retinal toxicity which can end up as irreversible retinopathy. Proper prevention is needed by recognizing risk factors and screening, as well as strict monitoring of drug use. I
Co-Authors Andrew Adiguna Halim Angelo Doniho Cisca Kuswidyati Devina Permatasari Felicia Kurniawan Ferdy Iskandara Giovani Faustine Ivana Beatrice Alberta Kristian Dernitra Laura Agnestasia Djunaedia Maria Vania Tri Ekaputri Monica Angelina Sidney Ganda Sigit Pradono Diptoadic Thendy Foraldy Vanessa Kuswanto