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All Journal Jurnal Dinamika Pengabdian (JDP) Jurnal Farmasi Galenika (Galenika Journal of Pharmacy)
Huriatul Masdar
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Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology

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PEMANFAATAN TEKNOLOGI BIOPORI UNTUK MENINGKATKAN DERAJAT KESEHATAN LINGKUNGAN DI DESA BULUHCINA KECAMATAN SIAK HULU, KABUPATEN KAMPAR Chandra, Fifia; Masdar, Huriatul
Jurnal Dinamika Pengabdian Vol. 6 No. 1 (2020): JURNAL DINAMIKA PENGABDIAN VOL. 6 NO. 1 OKTOBER 2020
Publisher : Departemen Budidaya Pertanian Fakultas Pertanian UNHAS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/jdp.v6i1.7964

Abstract

Buluhcina Village, Siak Hulu Subdistrict, Kampar Regency is located on the banks of the Kampar river. Flood occurs almost every year so that pools of water are formed. The behavior of the people of Buluhcina Village in processing the organic waste they produced remain poor. Therefore, there must be a way to overcome it by applying biopori technology in Buluhcina Village, Siak District, Kampar Regency. Counseling activities and training on household waste management were held in the Buluhcina Village Hall, Siak Hulu District, Kampar Regency on October 5th, 2019. The activity was attended by 16 participants. The result showed the increases the level of knowledge about organic household waste management after counseling, from 55.69 ± 10.216 to 72.44 ± 12.101 (p <0.002).   Keywords: Biopori infiltration holes, organic household waste management, organic waste.   ABSTRAK Desa Buluhcina Kecamatan Siak Hulu Kabupaten Kampar terletak di pinggiran sungai Kampar. Hampir setiap tahunnya Desa Buluhcina ini terjadi banjir. Jika banjir sudah surut maka akan terjadi genangan-genangan air pada halaman rumah masyarakat atau di lahan kosong. Selain itu jika terjadi hujan genangan-genangan air ini pasti banyak terjadi. Perilaku masyarakat desa Buluhcina dalam mengolah sampah organik yang mereka hasilkan tergolong buruk. Oleh karena itu perlu dilakukan cara untuk menanggulangi kondisi tersebut salah satunya dengan cara mengelola sampah rumah tangga organik dengan menerapkan teknologi lubang resapan biopori di Desa Buluhcina Kecamatan Siak Kabupaten Kampar. Kegiatan penyuluhan dan pelatihan pengelolaan sampah rumah tangga organik berlangsung di Balai Desa Buluhcina, Kecamatan Siak Hulu, Kabupaten Kampar pada tanggal 5 Oktober 2019. Kegiatan tersebut diikuri oleh 16 peserta. Analisis ketercapaian menunjukkan terjadinya peningkatan yang bermakna pada tingkat pengetahuan tentang pengelolaan sampah rumah tangga organik setelah penyuluhan, yaitu dari 55,69 ± 10,216 menjadi 72,44 ± 12,101 (p<0,002).   Kata kunci: Lubang resapan biopori, pengelolaan sampah rumah tangga organik, sampah organik.
Mangrove (Rhizophora sp.) Fruit Extract Inhibits Tumor Growth Factor (TGF)-β1 Expression in High Cholesterol Diet-Fed Rats: Ekstrak Buah Bakau (Rhizophora sp.) Menghambat Ekspresi Tumor Growth Factor(TGF)-β1 pada Tikus yang Mendapat Diet Tinggi Kolesterol Hamidy, Muhammad Yulis; Masdar, Huriatul; Winarto, Winarto
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 7 No. 3 (2021): (December 2021
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2021.v7.i3.15667

Abstract

Background: Atherosclerosis is a major finding in cardiovascular disease. One of the pro-fibrotic cytokines that play an important role in the atherosclerosis process is Tumor Growth Factor (TGF)-β1, where the presence of high TGF-β1 secretion due to hypercholesterolemia will trigger excessive collagen matrix formation. Objective: To analyze Rhizophora sp fruit extract effect on TGF-β1 expression in high cholesterol diet-fed rats. Material and Methods: Eighteen 10-week-old rats weighing 150-200 g were used in this study. These animals were grouped into 3 groups, each consisting of 6 rats. Group A (normal control) is a group of rats that received a normal diet. Group B (atherogenic control) received a diet that induces atherosclerosis (atherogenic diet). This diet contains 2% cholesterol, 5% goat fat, 0.2% cholic acid and standard diet up to 100%. Atherogenic diet was given for 3 days, and on the first day this group also received vitamin D3 700,000 IU/kg. Group C (treated), apart from receiving an atherogenic diet, was also given Rhizophora sp fruit extract 500 mg/kg body weight. The Rhizophora sp fruit extract effect on TGF-β1 expression was evaluated by immunohistochemical procedure. The area of ​​the expression is calculated using the ImageJ. Results: The results of this study indicate that the expression of TGF-β1 is higher in the group receiving the atherogenic diet than the normal control group (17.3 vs. 8.9; P=0.000). Rhizophora sp fruit extract reduced this expression remarkably (17.3 vs. 11.4; P=0.001). Conclusion: Rhizophora sp fruit extract inhibits the the expression of TGF-β1 in high cholesterol diet-fed rats.
Co-Authors Abd. Rasyid Syamsuri Dani Rosdiana Fifia Chandra Muhammad Yulis Hamidy Saputri, Pragita Ayu Winarto Winarto