Article Per Year (5 Year)
p-Index From 2020 - 2025
0.23
P-Index
This Author published in this journals
All Journal IJFAC (Indonesian Journal of Fundamental and Applied Chemistry)
Seni Metasari
Master Program, Department of Chemistry, Sriwijaya University
Biochemistry, Genetics & Molecular Biology Chemistry Environmental Science

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Study of Antioxidant Activities from Antihypertension Drug Plant of the Indralaya Area Seni Metasari; Muharni Muharni; Elfita Elfita; Heni Yohandini
IJFAC (Indonesian Journal of Fundamental and Applied Chemistry) Vol 5, No 1 (2020): February 2020
Publisher : IJFAC (Indonesian Journal of Fundamental and Applied Chemistry)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24845/ijfac.v5.i1.22

Abstract

Ogan ethnic population in Indralaya, Ogan Ilir District, South Sumatra was known to have used several types of plants, there are Swietenia mahagoni, Averrhoa carambola, Syzygium samarangense, Musa acuminata, Nymphaea rubra, Syzygium polyanthum, and Andrographis paniculata for the treatment of hypertension. But, scientific information has not yet been found secondary metabolites that are responsible for providing these activities. The study began with the extraction of methanol from the seven types of plants using methanol as a solvent. Each thick extract was tested for its activity using the 1,1-diphenyl-1-picryllhydrazyl (DPPH) method. The extract which showed the highest activity (methanol extract) was subsequently carried out in vitro antihypertension test using the Angiotencyn Converting Enzyme (ACE) method. Antioxidant test results showed that the methanol extract from S. samarangense stem bark had the highest antioxidant activity with IC50 was 83.06 μg/mL. Antihypertension test of methanol extract from S. samarangense stem bark obtained IC50 ACE was 61.56 μg/mL. Based on the IC50 value, it shows that S. samarangense stem bark has potential as a source of antioxidant compounds as well as a source of antihypertension compounds. Keywords: Syzygium samarangense, stem bark, antioxidant, antihypertension
Co-Authors Abd. Rasyid Syamsuri Elfita Elfita Heni Yohandini