Article Per Year (5 Year)
p-Index From 2021 - 2026
0
P-Index
This Author published in this journals
All Journal Dental Journal (Majalah Kedokteran Gigi)
Melanie Sadono Djamil
Biochemistry and Oral Biology Department, Faculty of Dentistry, Universitas Trisakti
Dentistry

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
The relation of periodontal diseases to systemic diseases Melanie Sadono Djamil; Boedi Oetomo Roeslan
Dental Journal (Majalah Kedokteran Gigi) Vol. 41 No. 4 (2008): December 2008
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (488.95 KB) | DOI: 10.20473/j.djmkg.v41.i4.p167-172

Abstract

Background: The relationship between systemic disorders and periodontal disease has been studied extensively. With few exceptions, it is more accurate to consider systemic diseases to be contributing factors in the pathogenesis of periodontal disease rather than the primary etiologic factors. The development of periodontal disease cannot be separated from the weakening of immunologic and immunopathological responses. Periodontal disease may enhance susceptibility to certain systemic diseases in several ways. Lipopolysaccharide (LPS) and Gram-positive bacteria in the biofilm and proinflammatory cytokines produced from inflamed periodontal tissues may enter the circulation system causing the development of certain systemic diseases. On the other hand, through immunologic mediators, certain systemic disease may enhance susceptibility to periodontal disease caused by the decrease of immune responses and the increase of proinflammatory cytokines. Purpose: The Purpose of this article is to review the immunologic aspect of two way relationship between systemic diseases and periodontal diseases. Review: This review studied the relationship between general health status, systemic diseases, and periodontal diseases through immunopathological responses and the weakening of the immune system in the periodontal tissue. Conclusion: there is a two-way relationship between periodontal diseases and systemic diseases.
Co-Authors Boedi Oetomo Roeslan