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Kus Harijanti
Departement of Oral Medicine, Faculty of Dental Medicine, Universitas Airlangga
Dentistry

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The management of oral candidosis in diabetic patient with maxillary Herpes Zoster Kus Harijanti; Dwi Setyaningtyas; Isidora KS
Dental Journal (Majalah Kedokteran Gigi) Vol. 41 No. 3 (2008): September 2008
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (400.032 KB) | DOI: 10.20473/j.djmkg.v41.i3.p132-136

Abstract

Background: Oral candidosis is an infection caused by mainly Candida albicans. Candida species are common normal flora in the oral cavity and have been reported to be present in 40% to 60% of the population. Candida is predominantly an opportunistic infectious agent. Infection frequency has increased because of the presence of both local and systemic risk factors. The elderly age and diabetes mellitus may decrease the amount of saliva (xerostomia) and potentially increase the risk of colonization and secondary infection by Candida. Herpes Zoster (HZ) is a manifestation of the reactivation of latent varicella zoster virus. It is characterized by unilateral, painful, vesicular rash with a dermatomal distribution. The clinical manifestations of this disease can erupt to the skin and mucous membrane. If maxillary nerve is involved, the lesion can appear on unilateral facial skin and oral mucous membrane. Purpose: The purpose of this paper is to report and discuss the difficulties in managing the oral candidosis in elderly patient (57 year old male) who suffered from maxillary Herpes Zoster and diabetes mellitus. Case management: At first, the patient was treated with 2% chlorhexidine gluconate and mycostatin oral suspension as topical antimycotic and reffered to dermathology clinic for viral infection treatment, however the oral candidosis did not improved. Subsequently, ketokonazole tablet was given three times daily for three weeks and regulated blood glucose level. In systemic antifungi (ketokonazole) treatment the oral candidosis disappeared. Conclusion: In this case, it is conclude that the management of oral candidosis are adequate, antiviral, blood glucose level regulating and systemic antifungal therapy.
Prevalence of xerostomia on type 2 diabetes mellitus in Hajj Hospital Surabaya Kus Harijanti; Bagus Soebadi; Irvanda Mulyaningsih
Dental Journal (Majalah Kedokteran Gigi) Vol. 40 No. 3 (2007): September 2007
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (119.852 KB) | DOI: 10.20473/j.djmkg.v40.i3.p136-139

Abstract

Diabetes Mellitus (DM) is a chronic disorder of carbohydrate, fat and protein metabolism. A defective or deficient of the insulin secretory, which is translated into impaired carbohydrate (glucose) use, is characteristic feature of DM, as the resultant is hyperglycemia. There is variability among patients, however, morphologic changes are likely found in arteries (atherosclerosis), basement membrane of the blood vessel wall tissues (micro angiopathy), kidneys (diabetic nephropathy), retina (retinopathy), nerves (neuropathy) and other tissues. If it involves salivary glands, the clinical sign is xerostomia. The type 2 of DM is caused by a combination of peripheral resistance to insulin action and an inadequate secretory response of the pancreatic b-cell. Approximately 80% to 90% of patients have type 2 diabetes. The purpose of this study was to determine the prevalence of xerostomia and its relation with level of blood glucose in type 2 DM. The data was taken using cross sectional method on the diabetic patients of Internal Medicine clinic, Hajj Hospital Surabaya from February to March 2006. The result that showed among 50 samples of the type 2 DM, the prevalence of xerostomia were 38 patients (76%). Most of the patients (32 patients = 84%) on bad regulation of DM with level of fasting glucose ≥ 126 mg/dl and level of post prandial glucose ≥ 180 mg/dl. The study showed that bad regulation of type 2 DM could develop complication on salivary glands, with xerostomia as the clinical sign.
Co-Authors Bagus Soebadi Dwi Setyaningtyas Irvanda Mulyaningsih Isidora KS