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All Journal PROSIDING SEMINAR NASIONAL CENDEKIAWAN MEDICINUS Jurnal Riset Ilmu Kesehatan Umum dan Farmasi

Ahmad Fiqri

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Author-ID : 3201591

Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Analisis In Silico Potensi Minyak Kedelai (Glycine max) dalam Terapi Dermatitis Atopik Primadhanty. R. S. Bhadra; Mardiana; Ahmad Fiqri; Ummi Rinandari; Didik H. Utomo; Muhammad Eko Irawanto
MEDICINUS Vol. 34 No. 2 (2021): MEDICINUS
Publisher : PT Dexa Medica

Soybean oil contains various bioactive phytochemicals such as phenolic acids, flavonoids, isoflavones, saponins, phytosterols and sphingolipids which might give benefit in the treatment of atopic dermatitis (AD). This study aimed to evaluate the soybean oil compounds using computational in silico analysis for the treatment of atopic dermatitis. The active compounds of soybean oil were extracted from the KNApSAcK database. Results showed that soybean oil might possess some potential bioactivity such as immunosuppressant, antiinflammatory, improves skin barrier function, antieczema and histamine inhibitor. The highest potential bioactivity of soybean oil was as antiinflammatory, with an average value of probable to be active (Pa) 0.684; while the high potency active compound is alpha-tocopherol (Pa: 0.956).

Koinfeksi Sifilis Sekunder, Condyloma Acuminata dan Human Immundeficiency Virus (HIV) pada Pria Homoseksual Ahmad Fiqri; Endra Yustin ES
MEDICINUS Vol. 35 No. 2 (2022): MEDICINUS
Publisher : PT Dexa Medica

Introduction: Men who have sex with men (MSM) have higher risk of contracting sexually transmitted infections (STIs) such as syphilis, one of chronic and systemic STI. HIV and HPV infection can be risk factors for syphilis infection, while coinfection between syphilis and HIV facilitates the course of the two diseases. Case: A 22-year-old homosexual man complained of red scaly patches on both palms and feet, no itching, hair loss and lumps in the genital area. Examination revealed nonscarring alopecia on occipital region, bilateral patches with multiple erythematous plaques partly confluent hyperpigmentation and an overlying scale on palmar and plantar region, also multiple nodule papules with pale red smooth surface on perineal region. The acetowhite examination at the verrucous lesion was positive. The results of the CD4 examination was 112 cells/µl, VDRL/RPR was reactive 1:256; and TPHA was also reactive >1:5,120. Histopathological examination of the skin showed the features of skin syphilis and condyloma acuminata. Immunohistochemistry test revealed brownish Spirochaeta. The patient was diagnosed with secondary syphilis coinfection, condyloma acuminata, and HIV. Conclusion: We found a case of MSM patient that was coinfected with secondary syphilis, condyloma acuminata, and HIV. HPV and HIV infection are often coexisting because they both increase the risk of sexually transmitted infections.

Co-Authors Alfan Hugo Didik H. Utomo Endra Yustin ES Kalbuana, Nawang MARDIANA Muhammad Eko Irawanto Primadhanty. R. S. Bhadra Syamsul Irham Ummi Rinandari

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