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All Journal Majalah Kedokteran Sriwijaya Sriwijaya Journal of Surgery
Abda Arif
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Health Professions Medicine & Pharmacology Nursing Public Health

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COMPARISON OF HONEY EFFECTIVNESS WITH SILVER SULFADIAZINE 1% ON THE FORMATION OF EPITHELIAL POST DEEP DERMAL BURNS INJURY AT RATS Chandra Boby Hadinata; Abda Arif; Irfannudin Irfannudin
Majalah Kedokteran Sriwijaya Vol 52, No 3 (2020): Majalah Kedokteran Sriwijaya
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36706/mks.v52i3.12512

Abstract

This study is an experimental animal study that assesses the difference in effectiveness of healing deep dermal burns using 1% honey and silver sulfadiazine. The subjects of this study were rats that had deep dermal burns on their backs which were then treated with 1% honey and silver sulfadiazine. Then the epithelialization thickness was measured using a microscope. In this study, the results showed that in the honey administration group epithelium occurred with an average of 1.111±0.298 or 49.42%, whereas in the silver sulfadiazine 1% cream group epithelium had occurred with an average of 1,100 ±0.336 or 50.57%. There was no statistically significant difference between honey epithelium with silver sulfadiazine cream 1% on the 4th day with a value of ? = 0.921. In the Honey giving group epithelium occurred with a mean of 1.496±0.225, meaning that the epithelium increased by 20.92 ± 5.57%. In the group giving 1% silver sulfadiazine cream epithelium occurred on the 7th day with a mean of 1.362±0.166, meaning that the epithelial increase was 16.12 ± 10.42%. There were no statistically significant differences on the 7th day epithelium with a value of p = 0.171. Comparison of 10th day Epithelial Thickness between Honey Giving Group and SSD cream 1%, In the Honey group, epithelium occurred with an average of 1.746 ± 0.314, meaning that the epithelium increased by 12.12 ± 2.02%, whereas in the silver sulfadiazine 1% group, epithelium occurred with an average of 1.758 ± 0.244, meaning that the epithelium increased by 12.12 25 ± 0.89%. There was no statistically significant difference in epithelium on the 10th day with a value of p = 0.926. Honey and Silver 1% sulfadiazine cream have the same effectiveness against epithelial formation in deep dermal burns. Giving honey can be recommended as a treatment for deep dermal burns because it has the effectiveness of epithelial formation in deep dermal burns. Further research needs to be done on the higher degree of burns as well as research on the side effects that may be caused during honey administration. Further studies standardize the composition and effective dose of honey for the treatment of burns so that it is used by the standard treatment standards for burns.
Predicting Burn Patient Mortality: A Comparative Analysis of the BOBI and R-Baux Scoring Systems Abda Arif; Ruli Robi Ferli; Theodorus
Sriwijaya Journal of Surgery Vol. 8 No. 1 (2025): Sriwijaya Journal of Surgery
Publisher : Surgery Department, Faculty of Medicine Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/sjs.v8i1.116

Abstract

Introduction: Burns represents a significant global health challenge, causing considerable morbidity and mortality. Accurate prognostication is crucial for optimal burn care management. This study compared the accuracy of the BOBI and R-Baux scores in predicting mortality among burn patients. Methods: This retrospective study analyzed data from 46 burn patients treated at Dr. Mohammad Hoesin General Hospital Palembang. Patient demographics, burn characteristics, and mortality outcomes were recorded. BOBI and R-Baux scores were calculated for each patient. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and Youden Index were determined for both scores. Agreement between the scores was assessed using the Kappa statistic. Statistical analysis was performed using SPSS v25. Results: The majority of patients were male (76.1%) and under 50 years old (84.8%). Fire burns (63%) and superficial-mid dermal injuries (32.6%) were most prevalent. The BOBI score demonstrated fair accuracy (sensitivity: 84.6%, specificity: 63.6%, PPV: 0.478, NPV: 0.913, Youden Index: 0.480). The R-Baux score showed lower sensitivity (76.9%) but higher specificity (78.8%) (PPV: 0.588, NPV: 0.896, Youden Index: 0.560). The Kappa test indicated good agreement between the two scores (κ = 0.783, p = 0.000). Conclusion: Both BOBI and R-Baux scores can be used to predict mortality in burn patients. The BOBI score demonstrated higher sensitivity, while the R-Baux score exhibited higher specificity. The choice of scoring system may depend on the specific clinical context and the relative importance of sensitivity and specificity.
Co-Authors Chandra Boby Hadinata Irfannudin Irfannudin Ruli Robi Ferli Theodorus