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Husein Albar
Department of Child Health, Faculty of Medicine, Hasanuddin University/ Wahidin Sudirohusodo Hospital, Makassar, Indonesia
Health Professions Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Public Health

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SPECTRUM AND OUTCOME OF PEDIATRIC RENAL DISEASES IN DR. WAHIDIN SUDIROHUSODO HOSPITAL MAKASSAR Husein Albar
Nusantara Medical Science Journal Volume 1 No. 2 April - Juni 2016
Publisher : Faculty of Medicine, Hasanuddin University.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/nmsj.v1i2.2212

Abstract

ABSTRACT Objectives: To find out thespectrum and outcome of renal diseases in children hospitalized in the pediatric ward of dr. Wahidin Sudirohusodo Hospital Makassar. Methods: We carried out a retrospective review of standard medial recordof all childrenhospitalizedinthe pediatric ward of the dr.Wahidin Sudirohusodo Hospital Makassar. Review was based on the final diagnosis on their medical records to investigate the spectrum and outcome of the pediatric renal diseasesfrom January 2009 to December 2013. Results: A total number of 9573 children were admitted during the study period, out of which 580 had renal diseases accounting for 16.5% of all pediatric admission. Age of the patients ranged from 10 months to 16.7 years with mean age of 7.39 years and majority of the cases aged 5-10 years (37.2%). Boys (55.3%)were more encountered than girls(44.7%) with a boy to girl ratio of 1.2:1 and most of the patients were in good nutritional status (48.6%). According to their final diagnosis, the commonness pediatric renal diseases in this hospital was Acute Post Streptococcal Glomerulonephritis (27.6%), followed by Nephrotic Syndrome (25.2%), Urinary Tract Infection (19.1%), and  Others are Acute Glomerulonephritis (8.3%), Acute Kidney Injury(5.1%), Chronic Kidney Injury(5.0%), Wilm’s Tumor(4.7%), Hydronephrosis (3.4%), Henoch-Schoenlein Nephritis (0.9%), and Lupus Nephritis (0.7%).  Length of stay of the patients was mostly in 7-14 days (46.0%) and varying from 3 up to 28 days. Mortality in pediatric patients of renal diseases in this study was 11.2% and usually in those entering the hospital with late deteriorating conditionand die before getting optimal treatment. Conclusions: In conclusion, our study shows that pediatric renal disease in the pediatric ward of dr. Wahidin Sudirohusodo Teaching Hospital Makassar accounts for 16.5%of all pediatric admission and APSGN was the commonest pediatric renal disease, followed by NS and UTI. It seems that spectrum of pediatric renal diseases in dr. Wahidin Sudirohusodo Hospital Makassar was relatively similar to that reported from other developing countries. Mortality in patients with pediatric renal diseases in our study was 11.2% and usually in those entering the hospital with late deteriorating condition and die before getting optimal treatment.  Key words: Spectrum, Outcome, Renal Disease, Children, Makassar.
Profile of Pediatric Nephrotic Syndrome in Wahidin Sudirohusodo Hospital, Makassar, Indonesia Husein Albar; Fadel Bilondatu
Cermin Dunia Kedokteran Vol 46, No 3 (2019): Nutrisi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v46i3.505

Abstract

Introduction: Nephrotic syndrome is a common and important pediatric chronic renal disease, characterized by massive proteinuria, hypoalbuminemia, edema and hypercholesterolemia. This study was to assess the profile of pediatric nephrotic syndrome at Wahidin Sudirohusodo Hospital Makassar over a 7-year period. Methods: A retrospective study on hospitalized nephrotic syndrome patients at pediatric nephrology ward in Wahidin Sudirohusodo Hospital Makassar from January 2011 to December 2017. Demographic, clinical and laboratory data were extracted from medical records. Results: A total of 142 children with nephrotic syndrome who fulfilled the inclusion criteria was analyzed. Age at onset ranged from 1.4 to 17.5 years (mean 8.5 years), the majority (66.2%) was 5 year-old and above, predominantly boy (66.2%) with a boy to girl ratio of 1,95:1 and well-nourished (56.3%). Upper respiratory infections were observed in 36.6% cases. The predominant clinical signs and symptoms were edema (100%), hypertension (26.8%). Patients with relapse were 56.3%, and the mortality was 2.12%. The prevalent laboratory findings were microscopic hematuria (50.7%), massive proteinuria (100%), hypoalbuminemia (100%), hypercholesterolemia (100%), and elevated serum creatinine (9.9%). Conclusion: The profile of pediatric nephrotic syndrome at Wahidin Sudirohusodo Hospital Makassar was similar to typical children nephrotic syndrome and did not significantly differ from other studies.Introduksi : Sindrom nefrotik adalah penyakit kronis anak yang sering dan penting di seluruh dunia, ditandai oleh proteinuria masif, hipoalbuminemia, edema dan hiperkolesterolemia. Studi ini untuk menentukan profil sindrom nefrotik anak di rumah sakit Wahidin Sudirohusodo Makassar. Metode : Penelitian retrospektif 7 tahun pada pasien sindrom nefrotik di bangsal nefrologi anak rumah sakit Wahidin Sudirohusodo Makassar dari bulan Januari 2011 sampaidengan Desember 2017. Data diambil dari rekam medik terdiri dari data demografi dan temuan klinis dan laboratorium. Hasil: Total 142 pasien sindrom nefrotik anak yang memenuhi kriteira inklusi dianalisis. Umur pasien saat onset mulai dari 1,4 sampai dengan 17,5 tahun dengan rerata umur 8,5 tahun. Kebanyakan berumur 5 tahun atau lebih (66.2%) didominasi pasien laki-laki (66,2%) dengan rasio jenis kelamin 1,95:1. Status gizi baik (56,3%). Infeksi saluran napas atas ditemukan pada 36,6% kasus. Gejala dan tanda klinis utama adalah edema (100%), hipertensi (26,8%), Relaps pada 56,3% kasus dan 2,12% pasien meninggal. Temuan laboratorium utama adalah hematuria mikroskopik (50,7%), proteinuria masif (100%), hipoalbuminemia (100%), hiperkolesterolemia (100%), dan peningkatan kreatinin serum (9,9%). Simpulan: Profil sindrom nefrotik anak di rumah sakit Wahidin Sudirohusodo Makassar pada umumnya serupa dan tidak berbeda bermakna dari penelitian lain. 
Co-Authors Fadel Bilondatu