Article Per Year (5 Year)
p-Index From 2021 - 2026
0.23
P-Index
This Author published in this journals
All Journal Nusantara Medical Science Journal
Muhammad Zaki Rahmani
Medical Faculty Hasanuddin University
Materials Science & Nanotechnology Neuroscience

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
The Potential of Rosuvastatin in Stabilizing Lipid Profile and Improving Clinical Outcomes in Covid-19 Patients with Coronary Heart Disease William Suciangto; Haerani Rasyid; Nada Indira Ramadhani Nasrum; Muhammad Zaki Rahmani
Nusantara Medical Science Journal Volume 6 Issue 1, January - June 2021
Publisher : Faculty of Medicine, Hasanuddin University.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/nmsj.v6i1.12243

Abstract

Introduction : The novel coronavirus disease (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), remains a global challenge since December 2019 cause by its severe symptoms and high mortality rate. Some comorbidities are associated with clinical outcomes in COVID-19 patients, one of them is cardiovascular disease, including coronary heart disease (CHD). Statins are popularly used as the lipid controller in CHD patients. Not only controlling the lipid profile, statins also can reduce the inflammation process in COVID-19 patients. This review aims to determine the activity of statins and its potential to improve the clinical manifestation of COVID-19 patients with CHD. Methods : The method used in this paper is to examine and review the literature journal that has been published last 10 years. Results : Recent studies have shown that statins capable to control the lipid, also lowering the LDL cholesterol and increasing the HDL cholesterol. And other trials have shown that statin also have ability to reduce the inflammation and inhibit further cell damage by binding mpro, a protease produced by SARS-COV2. Conclusions:  Based on those studies, we conclude that statins have the potential effect as adjuvant therapy for clinical improvement in COVID-19 patients with CHD.
Co-Authors Haerani Rasyid Nada Indira Ramadhani Nasrum William Suciangto