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All Journal IDJP (Indonesian Journal of Pharmaceutics)
Margaretha Efa Putri
Department of Pharmaceutics, Faculty of Pharmacy, Universitas Padjadjaran

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Cellulose Nanocrystals Preparation as Pharmaceuticals Excipient : a Review Margaretha Efa Putri; Anis Yohana Chaerunisaa; Marline Abdassah; Iman Rahayu
Indonesian Journal of Pharmaceutics Vol 2, Issue 2, May - August, 2020
Publisher : Universitas Padjadjaran (Unpad)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/idjp.v2i2.26422

Abstract

Cellulose nanocrystals is a cellulose derivates which has been widely researched and observed as an chemical agent. Different with cellulose that has been widely used as pharmaceutical excipient especially in solid dosage form, cellulose in nanocrystals form is not available in pharmaceutical grade. Cellulose nanocrystals have different characteristics and quality which is depend on its preparation including sourcing, isolation procedure, and hydrolysis reaction involved. This difference is very important to deeply observed its impact in pharmaceutical dosage form with different active ingredients. In addition, cellulose nanocrystals should meet FDA requirement as pharmaceutical excipient. This review  describe cellulose nanocrystals preparation and its characteristics, its application to active pharmaceutical ingredients, and its properties in order to meet FDA requirement.Keywords: Cellulose, nanocrystals, pharmaceutical excipient
Co-Authors Anis Yohana Chaerunisaa Iman Rahayu Marline Abdassah