Health problems tend to increase, mental health is an issue that most real improvement. Some physical illnesses can cause anxiety in a person. A person with a chronic disease, prone to anxiety sufferers Diabetes is one of them.  The purpose of this study is the effect of anxiety on blood glucose levels in people with diabetes mellitus in Surakarta Banyuanyar Regional Health Center. Hypothesis There is a positive effect of anxiety on blood glucose levels in people with diabetes mellitus in the PHC Banyuanyar Surakarta.  In this study sample was respondents with Diabetes Mellitus (DM) type 2 Surakarta region Banyuanyar Health Center. By sampling the total sampling with gauge Scale anxiety scale and blood glucose levels of people with Diabetes Mellitus (DM) Type 2.  Based on calculations using the computer program SPSS 15.0 for Windows obtained the value of r count (0.754)> r  table (0.339) or (p = 0.000 <0.05) so that Ha is accepted, it means a significant difference between the levels of anxiety blood glucose in patients with diabetes mellitus in the Greater Surakarta Banyuanyar Health Center.   Distribution results based on Blood Glucose Levels of respondents can be seen that the most dominant is the Blood Glucose Levels respondents in the category DM (â¥Â 200) that is equal to 16 or 47.1%.