Diabetes Mellitus is a group of metabolic diseases with characteristichyperglycemia that occurs due to abnormalities in insulin secretion, insulinaction or both. British Diabetic Association recommends that patients withdiabetes apply a similar diet to the vegetarian diet as vegetarians tend toconsume enriched carbohydrates and fibers.This research is a descriptive study observational analytic using cross sectionaldesign. This study describes the differences in levels of blood glucose and lipidprofile in patients with diabetes mellitus type II which were given a diet lacto ovovegetarian and the non-vegetarians. This study was conducted at the R.W.Monginsidi Manado Hospital forthe nonlacto ovo vegetarian, and at ManadoAdventist Hospital for thelacto ovo vegetarians diet.From the test resultsstatistically using unpaired T test for the Mean value or average fasting bloodglucose levels showed an average of each group, the non-vegetarian groupworth 179 while the lacto ovo value 138 with a value of 0,072 siq where> 0.05,which means there were no differences between the groups of non-vegetarianand lacto ovo vegetarian, kolesterol total (p=0,015), LDL (p=0,067), HDL(p=0,017), Trigliserida (p=0,026)The conclusion of this research shows no difference in blood glucose levelsforthe patients who were given diet lacto ovo vegetarian and the nonvegetarians.However, there are differences of Lipid Profile levels to the patientsgiven diet lacto ovo vegetarian and the non-vegetarian.