<![CDATA[The condition of a person is said to be obese or overweight is still a lot that can not distinguish, overweight is a weight that exceeds normal weight, while obesity is the excess fat accumulation in the body (Coal, 2010). According to WHO (2013), Overweight and obesity are the causes of noninfectious diseases. At least 2, 8 million adults die from Overweight or obesity each year. Determination of overweight used measurement Body Index (BMI) is by dividing body weight (kg) with height body (m2), (WHO, 2010).This study aims to identify the level of liver enzymes in employees with weight Overweight in environment Poltekkes Kemenkes Manado. The type of this research is laboratory survey with case control study design. The population of the study were employees who worked in Poltekkes Kemenkes Manado, sampling with Purposive sampling technique based on case and control clustering according to inclusive criteria and obtained a good sample number of Case and Control group respectively 30 respondents. An enzyme measurement apparatus using a Microlab 300 Photometer is performed in an accredited laboratory. Data were analyzed by univariate, bivariate using Chi-quare statistic test.The result of this research is P = 0.0024 on sGOT and P = 0.003 at sGPT where P value <0.05 means that there is a significant relationship between sGOT liver enzyme and sGPT employee poltekkes kemenkes manado with each Odd ratio at sGOT of 3.8 and sGPT 5.23 this means an odds of 4 times at higher sGOT values n people with an overweight BMT of the normal BMI, whereas at high sGPT values have a chance of 5 times of occurrence in people with an overweight BMI (BMT) over normal BMI]]>
