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Agustina Tri Pujiastuti
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Immunology & microbiology Public Health

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Studi Retrospektif: Vaginosis Bakterial Agustina Tri Pujiastuti; Dwi Murtiastutik
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 26 No. 2 (2014): BIKKK AGUSTUS 2014
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (127.243 KB) | DOI: 10.20473/bikk.V26.2.2014.1-7

Abstract

Latar belakang: Vaginosis bakterial (VB) adalah sindrom klinis akibat pergantian Lactobacillus spp. penghasil hidrogen peroksidase (HO) dalam vagina normal dengan bakteri anaerob konsentrasi tinggi, Gardnerella vaginalis dan Mycoplasma 22hominis. VB merupakan penyebab keluhan duh tubuh vagina dan keputihan berbau, namun 50% pasien VB tidak memberikan gejala apapun. Tujuan: Mengevaluasi gambaran umum kasus baru VB di Divisi Infeksi Menular Seksual (IMS) Unit Rawat Jalan (URJ) Kesehatan Kulit dan Kelamin RSUD Dr. Soetomo Surabaya periode tahun 2007-2011. Metode: Penelitian dilakukan secara retrospektif dengan melihat catatan medik kasus baru VB yang meliputi data dasar, anamesis, pemeriksaan fisik dan pemeriksaan penunjang. Hasil: Jumlah kasus baru VB adalah 35 pasien dari 33.201 (0,1%) kunjungan baru URJ Kesehatan Kulit dan kelamin RSUD Dr. Soetomo Surabaya, dengan kelompok usia terbanyak 25-44 tahun sebesar 26 (74,3%) pasien dan 31 pasien (88,6%) sudah menikah. Keluhan utama terbanyak berupa duh tubuh vagina tanpa keluhan subjektif yaitu sebanyak 16 (45,7%) pasien. Duh tubuh vagina terbanyak berbentuk serosa pada 25 (71,4%) pasien. Pada pemeriksaan laboratorium ditemukan clue cell pada 100% kasus. Obat yang paling banyak diberikan berupa metronidazol. Simpulan: Gambaran umum kasus baru VB di RSUD Dr. Soetomo Surabaya menunjukkan insidensi kecil, sebagian besar pada kelompok usia seksual aktif dan keluhan utama terbanyak yaitu duh tubuh vagina tanpa disertai keluhan subjektif lainnya.Kata kunci: vaginosis bakterial, keputihan, bau, clue cell.
Oral Hairy Leukoplakia in Patient with HIV/AIDS Agustina Tri Pujiastuti; Dwi Murtiastutik
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 28 No. 1 (2016): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (215.463 KB) | DOI: 10.20473/bikk.V28.1.2016.71-77

Abstract

Background: Oral hairy leukoplakia (OHL) is an asymptomatic white plaque with vertical corrugations most commonly found on the lateral borders of the tongue. It is caused by local infection of Epstein- Barr Virus (EBV). OHL is usually associated with immunocompromised condition, and mainly described in patients with human immunodeficiency virus (HIV). Purpose: to report a case of oral hairy leukoplakia in an HIV patient that is often misdiagnosed as oral candidasis. Case: A 44-years old female came to the Dermato-Venereology Outpatient Clinic of Dr. Soetomo General Hospital Surabaya with complaint of persistent asymptomatic whitish color on both borders of her tongue. History taking revealed that at first the whitish color appeared spreading on the tongue, but after taking antifungal treatment, only the lesion on the borders still persisted, all attempts to scrub off the lesion failed. There were also history of diarrhea, fever and cough for almost 1 month. Further examination of HIV antibody 3 method tests revealed reactive result with CD4+ count of 1 cel/uL. Physical examination revealed bilateral painless white well demarcated plaque with “hairy” like corrugated appearance on the lateral borders of the tongue. Discussion: From history, clinical findings, and the reactive HIV antibody examination, the patient was diagnosed with AIDS with oral hairy leukoplakia. The patient was treated with acyclovir 200 mg, 5 times daily. After 2 weeks of treatment, clearance was achieved. Conclusion: The establishment of OHL which oftenly mistaken as oral candidiasis has a diagnostic value for HIV infection. Systemic antiviral institution and antiretroviral (ARV) medications as prevention for recurrence gave satisfying result. Key words: oral hairy leukoplakia, HIV, acyclovir.
Co-Authors Dwi Murtiastutik