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All Journal Journal of Agromedicine and Medical Sciences Journal of Anesthesiology and Clinical Research
Alief Ilman Zaelany
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience

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Comparison of the Effectiveness of 10% Sulfur Soap and 2-4 Ointment as Single Treatment Alief Ilman Zaelany; Ida Srisurani Wiji Astuti; Ika Rahmawati Sutejo
Journal of Agromedicine and Medical Sciences Vol 3 No 3 (2017)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v3i3.6145

Abstract

Scabies disease caused by Sarcoptes scabiei var. hominis mites has become a problem in a whole world especially in developing countries like Indonesia. Scabies has a very contagious nature especially in places with dense population levels like Islamic boarding school. Permethrin which is a drug of choice for scabies has a fairly expensive price so it is less effective when used in mass treatment. In Indonesia, sulfur preparations, especially 10% sulfur soap and 2-4 ointment are easy to obtain because the price is affordable and available at the community health clinic. The purpose of this study is to know the difference in effectiveness of 10% sulfur soap and 2-4 ointment as a single treatment and combination on scabies disease. In this clinical trial study, treatment was performed on 3 groups, 10% sulfur soap group (n=36), 2-4 ointment group (n=36) and combination group (n=36). The examination was done on days 8, 15 and 22. Data analysis using SPSS version 23 with chi-square test. The results showed that the highest recovery rate was in combination group (week-1 (22,22%), week-2 (63,89%) and week-3 (94,44%)) followed by 2-4 ointment group (week-1 (11,11%), week-2 (72,22%) and week-3 (88,89%)) and 10% sulfur soap group (week-1 (2,78%), week-2 (52,78%) and week-3 (75,0%). The results of the analysis comparing the 10% sulfur soap group with the combination group showed p value on all consecutive examinations p=0,013, p=0,339 and p=0,022. In the comparison 2-4 ointment group to the combination group obtained p value on all examinations respectively p=0,206, p=0,448 and p=0,394. The conclusion is combination therapy had the highest cure rate and statistically significant (p=<0,05) was obtained in comparison of 10% sulfur soap to combination at week-1 and week-3 examination. Keywords: scabies, comparison of the effectiveness, 10% sulfur soap, 2-4 ointment, combination, Islamic boarding school
Determinants of Postoperative ICU Admission in the Elderly: A Prospective Multicenter Study of Elective Surgeries in Indonesia Alief Ilman Zaelany; Isngadi Isngadi; Taufiq Agus Siswagama; Buyung Hartiyo Laksono
Journal of Anesthesiology and Clinical Research Vol. 6 No. 2 (2025): Journal of Anesthesiology and Clinical Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/jacr.v6i2.809

Abstract

Introduction: The increasing global geriatric population presents significant challenges for surgical care, particularly regarding the allocation of Intensive Care Unit (ICU) resources. This study aimed to identify determinants of postoperative ICU admission among elderly patients in Indonesia, a setting with a rapidly aging demographic. Methods: We conducted a prospective, multicenter cohort study across 15 Indonesian hospitals from February to April 2021. Patients aged ≥60 years undergoing elective surgery were enrolled via consecutive sampling. Data on patient demographics, American Society of Anesthesiologists (ASA) physical status, Charlson Comorbidity Index (CCI), and type of anesthesia (general vs. regional) were collected. The primary outcome was postoperative ICU admission. Multivariate logistic regression was used to identify independent predictors. Results: Of 893 patients enrolled, 18.8% required postoperative ICU admission. The final multivariate model revealed that a higher ASA physical status was the strongest predictor of ICU admission (Odds Ratio [OR] 4.13; 95% CI 2.88-5.92; p < 0.001). The administration of general anesthesia was also independently associated with a significantly increased likelihood of ICU admission compared to regional anesthesia (OR 2.77; 95% CI 1.83-4.19; p < 0.001). While the CCI was a significant factor in unadjusted analyses, its effect was attenuated after inclusion of the ASA score. Conclusion: ASA physical status and the choice of general anesthesia are powerful, independent determinants of postoperative ICU admission in the Indonesian geriatric surgical population. These findings highlight the critical role of preoperative physiological assessment and suggest that the choice of anesthetic technique has significant implications for postoperative resource needs.
Co-Authors Buyung Hartiyo Laksono Ida Srisurani Wiji Astuti Ika Rahmawati Sutejo Isngadi isngadi Taufiq Agus Siswagama