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All Journal SCIENTIA JOURNAL PRIMER (Prima Medical Journal) Jurnal EduHealth
Nadya Nazimuddin Putri
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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Uji Aktivitas Antibakteri Madu Alami Dan Olahan Terhadap Bakteri Staphylococcus Aureus Nadya Nazimuddin Putri; Cut Bueleun Maulida
PRIMER (Prima Medical Journal) Vol. 5 No. 1 (2020): Edisi April
Publisher : Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/pmj.v3i1.984

Abstract

Madu selama ini digunakan sebagai pengobatan alami karena memiliki efek antibakteri seperti pH yang rendah, hidrogen peroksida, dan memiliki aktivitas air yang rendah sebagai penghambat pertumbuhan bakteri. Penelitian ini bertujuan untuk mengetahui efektivitas madu alami dan olahan terhadap pertumbuhan Staphylococcus aureus. Metode yang digunakan adalah metode difusi cakram pada media NA. Madu yang digunakan merupakan jenis madu alami dan olahan dan dibuat dalam berbagai seri konsentrasi (25, 50, 75, dan 100)%. Untuk kontrol positif digunakan cakram antibiotik amoxicillin dan kontrol negatif menggunakan akuades. Model penelitian yang digunakan adalah penelitian eksperimental secara in vitro. Hasil penelitian menunjukkan bahwa pemberian madu alami dan olahan memiliki aktivitas antibakteri terhadap Staphylococcus aureus dengan diameter zona hambat oleh madu alami sebesar (27, 29.4, 32.1, dan 36.2)mm, madu olahan (6, 18.36, 30.33, dan 33.66)mm, kontrol positif (32.8)mm dan kontrol negatif (0)mm. Dapat disimpulkan bahwa madu alami dan olahan memiliki daya untuk menghambat pertumbuhan Staphylococcus aureus.
Test of the Effectiveness of Moringa Oleifera Leaf Extract Cream on the Healing Process of Cut Wounds on the Skin Surface of Male Wistar Rats (Rattus Norvegicus) Triastuti, Yulia; Nadya Nazimuddin Putri; Muhammad Nawal Hasya
Jurnal EduHealth Vol. 14 No. 04 (2023): Jurnal eduHealt, 2023, December
Publisher : Sean Institute

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Abstract

Everyone there must have been injured in some way. Moringa Oleifera leaves have significant antioxidant activity and are just one of many plant-based treatments used to treat pain and speed wound healing. This study aims to ascertain if a cream made from the extract of moringa leaves (Moringa oleifera) accelerates the recovery of damages caused by cuts. This study strategy employs an actual or laboratory experimental design based on a pre-post test with a control group. Twenty adult male Wistar rats (Rattus norvegicus) were used. Mice were acclimatized, phytochemicals were screened, and treatment and monitoring were performed using dermapen wounds during the investigation. The Kolmogorov-Smirnov test, One-Way Analysis of Variance (ANOVA), and LSD post hoc Test were used to examine the research data in SPSS. Results from a 14-day study on the effects of a cream containing Moringa leaf extract on the wound healing of male Wistar rats (Rattus norvegicus) led researchers to this conclusion. In a recent phytochemical study, flavonoids, saponins, tannins, and alkaloids, known to have therapeutic benefits due to their high antioxidant content, were found in Moringa leaf extract. The secondary metabolite chemicals found in Moringa leaf extract significantly affected wound healing, with the best effects shown at an extract level of 10%.
Pengaruh Penggunaan APD dan Formula Emulsi terhadap Dermatitis Kontak Akibat Kerja pada Pekerja Batik di Muaro Jambi Nadya Nazimuddin Putri
SCIENTIA JOURNAL Vol. 13 No. 2 (2024): SCIENTIA JOURNAL
Publisher : Universitas Adiwangsa Jambi

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Abstract

Occupational contact dermatitis remains a prevalent health issue among batik workers due to repeated exposure to irritants and allergens, particularly from dyes and chemical fixatives. This study aimed to evaluate the effect of personal protective equipment (PPE) usage and the application of an emulsion-based formula in preventing occupational contact dermatitis among batik artisans in Muaro Jambi. A quasi-experimental pretest-posttest control group design was employed involving 60 batik workers divided into four groups: control, PPE only, emulsion only, and PPE with emulsion. The incidence and severity of contact dermatitis were assessed using the Hand Eczema Severity Index (HECSI) and patch testing over a 4-week period. Results demonstrated a statistically significant reduction in dermatitis symptoms in the PPE and emulsion combination group compared to the other groups (p<0.05). The use of both PPE and emulsion provided synergistic protection against irritant exposure and improved skin barrier function. This study underscores the importance of integrated preventive strategies combining physical barriers and topical protectants to reduce occupational dermatoses in traditional industries.
Co-Authors Cut Bueleun Maulida Muhammad Nawal Hasya Triastuti, Yulia