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All Journal Bioscientia Medicina : Journal of Biomedicine and Translational Research Bioscientia Medicina : Journal of Biomedicine and Translational Research
Khairil Pahmi
Department of Pharmacy, Diploma of Pharmacy, Faculty of Health Science, Universitas Nahdlatul Wathan Mataram, West Nusa Tenggara, Indonesia
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Neuroscience

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Effect of Leafflower (Phyllanthus niruri Linn.) treatment on kidney and uterus in sodium chloride -induced fibrotic rats Khairil Pahmi; M. Sidratullah
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 5 No. 3 (2021): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bsm.v5i3.187

Abstract

Background. Phyllanthus niruri (local name : meniran) extract is utilized in treating kidney and uterus disease. Effects of ethanol extract of P. niruri on kidney and uterus of 2% NaCl triggered fibrotic rats had been studied. Aim of Study. Aim of this study to explore the effect of leafflower (Phyllanthus niruri Linn.) treatment on kidney and uterus in 2% NaCl - induced fibrotic rats. Methods. Wistar rats were challenged with 2% NaCl in drinking water to induce fibrotic kidney and uterus. Phyllanthus niruri extract (200 mg/kg) was given orally for 4 weeks. Matrix extracellular abundance was determined by HE Staining and measured by METAVIR Fibrosis Score. The results of this study were assayed by SPSS 16. Results. P. niruri extract was potent to reduce the matrix extracellular in 2% NaCl-induced rats compared to control group (p<0.05). Conclusion. P. niruri extract was potent to decrease the matrix extracellular in the kidney and uterus of the rats.
The Effect of Meniran Herbs Extract (Phyllanthus niruri Linn) on The Histological Spectrum of The Uterus and Oviduct Rats (Rattus Norvegicus) Rosa Mutianingsih; Khairil Pahmi
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 5 No. 1 (2021): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bsm.v5i1.211

Abstract

Background The use of plants as natural medicinal ingredients isincreasingly in demand by the public because the plants are consideredto have lower negative effects than chemical drugs. The effect of mineranherbs extract (Phyllanthus niruri Linn) on the histological spectrum of theuterus and oviduct rat (Rattus Norvegicus) had been studied.Aim ofStudy Aim of this study to explore the effect of meniran herbs extract(Phyllanthus niruri Linn) on the histological spectrum of the uterus andoviduct rat (Rattus Norvegicus) Methods Wistar rats have been challengedwith 2% NaCl in drinking water to result in fibrotic uterus and oviduct.Phyllanthus niruri extract (200 mg/Kg) turned into given orally for 4weeks. Matrix extracellular abundance turned into decided via way ofmeans of HE Staining and measured via way of means of METAVIRFibrosis Score. The result of this examine have been assayed via way ofmeans of SPSS 16. Results P. niruri extract was potent to reduce thematrix extracellular in 2% NaCl-induced rats compared to control group(p<0.05) in uterus. Meanwhile, P. niruri extract was not able to decreasethe matrix extracellular in 2% NaCl-induced rats compared to controlgroup (p>0.05) in oviduct. Conclusion P. niruri extract was potent todecrease the matrix extracellular in the uterus of the rats, but in oviduct.
Effect of Leafflower (Phyllanthus niruri Linn.) treatment on kidney and uterus in sodium chloride -induced fibrotic rats Khairil Pahmi; M. Sidratullah
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 5 No. 3 (2021): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bsm.v5i3.187

Abstract

Background. Phyllanthus niruri (local name : meniran) extract is utilized in treating kidney and uterus disease. Effects of ethanol extract of P. niruri on kidney and uterus of 2% NaCl triggered fibrotic rats had been studied. Aim of Study. Aim of this study to explore the effect of leafflower (Phyllanthus niruri Linn.) treatment on kidney and uterus in 2% NaCl - induced fibrotic rats. Methods. Wistar rats were challenged with 2% NaCl in drinking water to induce fibrotic kidney and uterus. Phyllanthus niruri extract (200 mg/kg) was given orally for 4 weeks. Matrix extracellular abundance was determined by HE Staining and measured by METAVIR Fibrosis Score. The results of this study were assayed by SPSS 16. Results. P. niruri extract was potent to reduce the matrix extracellular in 2% NaCl-induced rats compared to control group (p<0.05). Conclusion. P. niruri extract was potent to decrease the matrix extracellular in the kidney and uterus of the rats.
The Effect of Meniran Herbs Extract (Phyllanthus niruri Linn) on The Histological Spectrum of The Uterus and Oviduct Rats (Rattus Norvegicus) Rosa Mutianingsih; Khairil Pahmi
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 5 No. 1 (2021): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bsm.v5i1.211

Abstract

Background The use of plants as natural medicinal ingredients isincreasingly in demand by the public because the plants are consideredto have lower negative effects than chemical drugs. The effect of mineranherbs extract (Phyllanthus niruri Linn) on the histological spectrum of theuterus and oviduct rat (Rattus Norvegicus) had been studied.Aim ofStudy Aim of this study to explore the effect of meniran herbs extract(Phyllanthus niruri Linn) on the histological spectrum of the uterus andoviduct rat (Rattus Norvegicus) Methods Wistar rats have been challengedwith 2% NaCl in drinking water to result in fibrotic uterus and oviduct.Phyllanthus niruri extract (200 mg/Kg) turned into given orally for 4weeks. Matrix extracellular abundance turned into decided via way ofmeans of HE Staining and measured via way of means of METAVIRFibrosis Score. The result of this examine have been assayed via way ofmeans of SPSS 16. Results P. niruri extract was potent to reduce thematrix extracellular in 2% NaCl-induced rats compared to control group(p<0.05) in uterus. Meanwhile, P. niruri extract was not able to decreasethe matrix extracellular in 2% NaCl-induced rats compared to controlgroup (p>0.05) in oviduct. Conclusion P. niruri extract was potent todecrease the matrix extracellular in the uterus of the rats, but in oviduct.
Co-Authors M. Sidratullah Rosa Mutianingsih