Mahendra Ilmi S Matondang
Department of Biotechnology, FBIM, Universiti Sultan Zainal Abidin, Kuala Terengganu, Malaysia

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TLC Profiling of Leaves Extracts of Some Aloe Threatened Species Endemic to Madagascar for Their Antioxidant Activity Rokiman Letsara; Rigobert Andrianantenaina; Gédéon Ngiala Bongo; Colette Masengo Ashande; Mahendra Ilmi S Matondang; Koto-te-Nyiwa Ngbolua; Baholy Robijaona Rahelivololoniaina
Britain International of Exact Sciences (BIoEx) Journal Vol 2 No 3 (2020): Britain International of Exact Sciences Journal, September
Publisher : Britain International for Academic Research (BIAR) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/bioex.v2i3.304

Abstract

The World Health Organization reported that at least 80% of populations rely on traditional medicine and medicinal plants for their primary health care. Due to their phytochemical compounds, the plants of the Aloe genus are reported to have high potential antiCovid-19 (and antioxidant properties. The aim of this study is to evaluate the in vitro antioxidant activity of some Malagasy endangered species of Aloe genus. The ethanolic extract of few Aloe of Madagascar leaf extracts was fractionated by liquid-liquid partition using hexane. In total 18 different fractions from 9 species have been used to determine their antioxidant activity through in vitro model by using 2,2-Diphenyl-1-picrylhydrazyl (DPPH) assay. Both hexanic extract and aqueous extract displayed antioxidant activities in four species. The most evident antioxidant activity was expressed by A. helenae.
A Mini-Review on the Phytochemistry and Pharmacology of the Plant Carica Papaya L. (Caricaceae) Clement Inkoto Liyongo; Colette Masengo Ashande; Clarisse Falanga Mawi; Blaise Membo wa Mbembo; Jean-Jacques Amogu Domondo; Mahendra Ilmi S Matondang; Jean-Pierre Kayembe Kayembe; Pius Tshimankinda Mpiana; Koto-te-Nyiwa Ngbolua
Britain International of Exact Sciences (BIoEx) Journal Vol 2 No 3 (2020): Britain International of Exact Sciences Journal, September
Publisher : Britain International for Academic Research (BIAR) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/bioex.v2i3.306

Abstract

Medicinal plant is an important element of indigenous medical systems all over the world. The ethno botany provides a rich resource for natural drug research and development. Carica papaya is used in Traditional Medicine since a long time. Our investigations started by a search of relevant literature on the plant species. Databases such as Science direct, PubMed, Google Scholar and Scopus were used successively to retrieve the articles on C. papaya. The chemical structures of isolates compounds from this plant were drawn using ChemBioDraw Ultra 12.0 software package. Finally, bibliographical references were made using bibliographical software "Mendeley". Results show that the plant C. papaya contains various secondary metabolites, minerals and vitamins. The plant species is reported to possess various pharmacological properties like anti-oxidant, anti-inflammatory, antibacterial, anti-diabetic, anti-hyperlipidemic, larvicidal effects, etc. These pharmacological activities could due to the presence of various phytochemicals present in this plant species. The present review can therefore help inform future scientific research towards the development of novel drugs of relevance from C. papaya to combat various ailments including Sickle cell disease.