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All Journal IJFAC (Indonesian Journal of Fundamental and Applied Chemistry) Britain International of Exact Sciences Journal (BIoEx Journal)
Koto-te-Nyiwa Ngbolua
Department of Environment, Faculty of Science, University of Gbado-Lite, Gbado-Lite, Democratic Republic of the Congo
Biochemistry, Genetics & Molecular Biology Chemistry Environmental Science Mathematics Medicine & Pharmacology Physics

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Survey on the Industrial Logging Activities in the Businga Territory (Nord-Ubangi Province) in Democratic Republic of the Congo) Koto-te-Nyiwa Ngbolua; Armand Endowa Doikasiye; Modeste Ndaba Modeawi; Ruphin Djolu Djoza; Amédée Gbatea Kundana; Colette Masengo Ashande; Clarisse Falanga Mawi; Ange Thijenira Loketo; Emmanuel Moke Lengbiye; Jonas Nagahuedi Mbongu Sodi; Muhammad Ridwan
Britain International of Exact Sciences (BIoEx) Journal Vol 3 No 1 (2021): Britain International of Exact Sciences Journal, January
Publisher : Britain International for Academic Research (BIAR) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/bioex.v3i1.382

Abstract

The aim of this study was to investigate industrial logging in Businga Territory. The survey was carried out by means of a questionnaire addressed to 235 people including 150 men (64%) and 85 women (36%) between 31 and 100 years of age, on the basis of free and informed consent. It emerged from this study that 110 subjects out of the 235 (46.8%) were from SICOTRA company and its surroundings and 125 respondents (53.2%) belonged to from KKF company and its surroundings. Of the 235 people surveyed, only 104 (or 44.3%) were workers from two companies, the rest were heads of groups, capitas, local notables and those who had not worked in either company. 44.6% of the respondents had a primary level followed by 31.9% (or 75 people) with a secondary level. There are 55 illiterate people (23.4%). No university executives were met in the area during the survey. The logging by these two companies (KKF: from 1949 to 1998 (49 years of exploitation) and SICOTRA: from 1980 to 1998 (18 years)) has caused enormous destruction of the ecosystem and the population is today confronted with multiple difficulties and problems of supply of Non Timber Forest Products (caterpillars, snails, mushrooms, Cola acuminata, etc.) and the erosion of biodiversity. Of the 17 forest species exploited in this Sector, 03 have totally disappeared: Diospyros crassiflora Hiern, Nauclea diderrichii (De Wild.) Merr. and Prioria balsaminfera (Vermoesen) Breteler. The majority contacted had no notion of protecting the forest (67.2% vs. 32.8%); the population had no notion of drawing up specifications (95 vs. 5%). The results revealed that the indigenous population did not benefit from their forest, nor did they benefit from basic social infrastructures of community interest. In order to remedy this situation, a good regulation of the forestry exploitation code, the popularization of the new forestry code and the elaboration of specifications in collaboration with local communities are necessary to correct this situation in the future.
Survey on the Production of Traditional Bioenergy in the Democratic Republic of the Congo: The Case Study of Kwilu Province Masens Da-Musa Y.B.; Koto-te-Nyiwa Ngbolua; Briki C. Kakesa; Muhammad Ridwan
Britain International of Exact Sciences (BIoEx) Journal Vol 3 No 2 (2021): Britain International of Exact Sciences Journal, May
Publisher : Britain International for Academic Research (BIAR) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/bioex.v3i2.432

Abstract

The present research has been carried out in three different groupings, namely Mudikwiti, Tanganga and Nkata in Kwilu province, in the Democratic Republic of the Congo. 165 coalmen from eighteen villages have been considered as the sample used in this work. They are selected from all social strata, and their ages vary from 18 to 30 years old and from 44 to 56 years old. They have made 21,899 ovens, among which there were 12, 287 ovens of small dimensions, that is, 1 m x 6 m x 3 m, and 9,612 ovens of big dimensions: 6 m x 20 m x 3 m. They have cut 196,694 trees of different species to fill in the two kinds of ovens, say 99,984 trees for filling in small ovens and 96,710 trees to fill in big ovens. On the whole, they have produced 852,708 sacks of charcoal per year. The Nkata grouping, with its 11 villages, has produced 129,600 sacks of 45 kilograms, divided as follows: 14,400 sacks from the small dimension ovens and 115, 200 sacks from the big dimension ovens.
Survey on Knowledge and on some Cases of Monkeypox: A Zoonotic Disease Endemic to Ubangian Eco-region of Democratic Republic of the Congo Koto-te-Nyiwa Ngbolua; Ruphin Djolu Djoza; Jeff Iteku Bekomo; Colette Masengo Ashande; Clarisse Falanga Mawi; Emmanuel Kitete Mulongo; Dorothée Tshilanda Dinangayi; Damien Sha Tshibey Tshibangu; Muhammad Ridwan; Pius T. Mpiana
Britain International of Exact Sciences (BIoEx) Journal Vol 4 No 3 (2022): Britain International of Exact Sciences Journal, September
Publisher : Britain International for Academic Research (BIAR) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/bioex.v4i3.737

Abstract

The aim of this study was to investigate knowledge on Simian Orthopoxvirosis or Monkeypox in 180 people (129 males and 51 females) using the stratified probability sampling method. The majority of the respondents were (are): 35-50 years old (45.00%), with secondary education (43.33%), farmers (40.56%) and married (80.00%). The disease appears every year, thus demonstrating its endemic nature (98.33% of the respondents); 58.3% of the respondents said that the disease appears very often during the dry season, on the contrary, 40% of the respondents said that the disease appears during the rainy season. However, 1.7% of respondents said that the disease occurs every other season. The majority of respondents (81.1%) said that the cause of the disease is the consumption of bush meat, followed by wild vegetables (3.3%), fish (2.8%), livestock (2.2%) and caterpillars (1.7%) respectively. 65.2% of the respondents use Manihot esculenta to treat the disease locally, and followed by the leaves and wine of Raphia sese (13%), Morinda morindoides (13%) and Myrianthus arboreus (8.7%). Between January 17 and September 10, 2020, 40 cases of monkey pox were admitted to HGR of Businga (Maximum age: 42 years, minimum age: 1 year, average age: 13.3 years). 28 patients were male and 12 female. It is therefore advisable that surveillance be organized in wild animals and bush meat exposed on the market to ensure that they are not contaminated with Monkeypoxvirus. It is thus needed to establish a veterinary laboratory in Nord-Ubangi Province.
In silico screening of natural compounds from Jatropha curcas (Euphorbiaceae, Linn) and Jatropha gossypifolia (Euphorbiaceae, Linn) against SARS-CoV2, a COVID-19 main protease, using molecular docking approach Emmanuel Kitete Mulongo; Jason T Kilembe; Gedeon Ngiala Bongo; Koto-te-Nyiwa Ngbolua; Dorothée Tshilanda Dinangayi; Damien Sha Tshibey Tshibangu; Pius T Mpiana
IJFAC (Indonesian Journal of Fundamental and Applied Chemistry) Vol 7, No 3 (2022): October 2022
Publisher : IJFAC (Indonesian Journal of Fundamental and Applied Chemistry)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24845/ijfac.v7.i3.148

Abstract

SARS-Cov2, the COVID-19 main protease is set to be a good target for potential inhibitors especially from plants. 6LU7, the crystal structure of COVID-19 has been used for docking with natural compounds from Jatropha curcas and Jatropha gossypifolia. The following compounds identified within J. curcas have given good binding affinities than Azythromycin (control sample): 2-methyl anthraquinone, Curcusone D, Palmarumycin CP1, Apigenin, Jatropholone A, Jatropholone B, Spirocurcasone and Multidione. The best score is for Palmarumycin CP1 -8.2 Kcal/mol. All these compounds are R05 satisfied, good HIA scores and good pharmacokinetic properties. In J.gossypifolia, 2,24,25-Trihydroxylanosta-1,7-dien-3-one ; Cleomiscosin A, Citlalitrione, Gossypifan, Jatrophenone, Jatropholone A, Jatropholone B, Gadain, Gossypidien, Falodone and Gossypiline are having good binding affinities than Azythromycin (control sample). The best score is for Cleomiscosin A -8.2 Kcal/mol. All these compounds are R05 satisfied, good HIA scores and good pharmacokinetic properties. This study has shown anti-COVID-19 potential of these two plants.
Co-Authors Amédée Gbatea Kundana Ange Thijenira Loketo Armand Endowa Doikasiye Briki C. Kakesa Clarisse Falanga Mawi Colette Masengo Ashande Damien Sha Tshibey Tshibangu Dorothée Tshilanda Dinangayi Emmanuel Kitete Mulongo Emmanuel Moke Lengbiye Gedeon Ngiala Bongo Jason T Kilembe Jeff Iteku Bekomo Jonas Nagahuedi Mbongu Sodi Masens Da-Musa Y.B. Modeste Ndaba Modeawi Muhammad Ridwan Pius T Mpiana Pius T. Mpiana Ruphin Djolu Djoza