Article Per Year (5 Year)
p-Index From 2020 - 2025
0
P-Index
This Author published in this journals
All Journal Indonesian Journal of Cardiology
Sunarya Soerianata
JKI
Health Professions Medicine & Pharmacology

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Hubungan Inhibisi Agregrasi Platelet setelah Pemberian Eptifibatide dengan Kejadian Kardiovaskular Mayor pada Pasien Infark Miokard Akut Elevasi Segmen ST yang Menjalani Intervensi Koroner Perkutan Primer Elisa Feriyanti Pakpahan; Sunarya Soerianata; Nur Haryono
Jurnal Kardiologi Indonesia Vol. 35, No. 1 Januari - Maret 2014
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v35i1.372

Abstract

Background: Eptifibatide, an inhibitor of glycoprotein IIb/IIIa administered as adjunctive therapy to reperfusion therapy Primary PCI in STEMI patients. Persistently high platelet reactivity was found in patients who experienced recurrent atherothrombotic events during antiplatelet therapy.Objective: To evaluate the level of platelet inhibition after eptifibatide therapy and to assess the relation between level of platelet inhibition and Major Cardiaovascular event (MACE).Methods: Platelet function test by Multiplate analyzer was performed in STEMI Patients who undergone Primary-PCI, 10 minutes after a bolus of eptifibatide. MACE were prospectively monitored during hospitalization and the incidence of MACE correlated with the measured level of platelet inhibition.Results: From 99 subjects, approximately 55% of the subjects were non-responders (high platelet reactivity). 18 patients experienced MACE, most were heart failure (8 people), malignant arrhythmias (3 people), recurrent angina (2 people), stroke (2 people) and reinfarction, infections and major bleeding each 1 person. 12 subjects experienced MACE was from the non-responder group and 8 subjects from the responder grup. The study was found that the level of platelet inhibition wasn’t an independent predictor for the risk of MACE.Conclusion: Less achieved therapeutic effects of platelet Inhibition (non-responders) was found in the majority (55%) subjects. Different level of platelet inhibition wasn’t an independent predictor for the risk of MACE.
Sistem Skor Baru untuk Memprediksi Kejadian Perdarahan pada Pasien Infark Miokard Akut dengan Elevasi Segmen ST yang Dilakukan Intervensi Koroner Perkutan Primer Wisnu A Widodo; Sunarya Soerianata; Andang H Joesoef; Ganesya M Harimurti
Jurnal Kardiologi Indonesia Vol. 34, No. 4 Oktober - Desember 2013
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v34i4.380

Abstract

Background Acute myocardial infarction still become one of the leadingmortality cause in the world. Among these patients, ST elevation myocardialinfartion (STEMI) has the greatest mortality rate among other type ofMyocardial Infarction. When a myocard infarct patient have bleeding events,mortality rate greatly increased. Up until now, there is no specific bleedingrisk assessment tool to predict bleeding events in STEMI patient.Methods A retrospective cohort study, done in National Cardiovascular CenterHarapan Kita, Jakarta in STEMI patients underwent Primary PercutaneousCoronary Intervention (PPCI). Bleeding event was defined according to definitionby Bleeding Academic Research Consortium (BARC) – European Societyof Cardiology, 2011. Categories for data obtained was basic characteristics,clinical examinations, initial therapies, lab results, x-ray, PPCI procedures, andin hospital treatments. Statistical analysis was done using multivariat analysisusing logistic regression method and then converted to a scoring system.Results 579 sampels fit the inclusion and exclusion criteria. Bleeding eventoccured in 42 patients (7.3%). Indonesia bleeding score (Range 1-100) wascreated by assignment of variables that included in the final model accordingto their Odds Ratio (OR) values. Those variables are: female gender(OR 2.91, CI 1.23-6.91), Killip class 3 / 4 (OR 5.64, CI 2.27-14.03), Age ?62 y.o (OR 2.19, CI 1.00-4.83), White blood cell >12.000 (OR 2.12, CI0.95-4.73), Creatinine >1.5 (OR 2.17, CI 0.95-4.96), Body Mass Index ?25 (OR 1.71, CI 0.83-3.51), Multiple coronary lesion (OR 1.95, CI 0.83-4.54), Femoral access (OR 2.33, CI 0.77-7.01), and TPM implantation (OR3.21, CI 1.28-8.07). These variabels was converted into two type of scoringsystem. The INA-1 contains all of the variables, and INA-2 minus variablesrelated to interventional result and procedures.Conclusion Indonesia bleeding score quantifies risk for in-hospital bleedingevent in STEMI patients underwent PPCI, which enhances baseline riskassessment for STEMI care.
Co-Authors Andang H Joesoef Elisa Feriyanti Pakpahan Ganesya M Harimurti Nur Haryono Wisnu A Widodo