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Singh P
Nepalgunj Medical College
Medicine & Pharmacology

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SEROPREVALENCE OF HEPATITIS-B VIRUS IN MID AND FAR WESTERN REGION IN NEPAL S, Khan; P, Singh; A. H., Siddiqui; M, Ansari
INDONESIAN JOURNAL OF BIOMEDICAL SCIENCES Vol 6 No 2 (2012): Indonesian Journal of Biomedical Sciences
Publisher : Udayana University

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Abstract

Hepatitis B is significant health problems that might involve the late sequel of liver cirrhosis and hepatocellular carcinoma. The present study aimed to know the seroprevalence of hepatitis B virus (HBV) in mid and far western region in Nepal with various clinical conditions.This was a retrospective study conducted in mid and far western region in Nepal, which was performed in the Central Laboratory of Microbiology at Nepalgunj Medical College and Teaching Hospital, Banke, Nepal during the period of September 2010 to April 2012. The serum samples were tested for Hepatitis B surface Antigen (HBsAg) by Sandwich immunoassay. Total 7010 patients including 43.72% male and 56.28% female were tested for HBsAg. Of them, 135 were positive and 6875 were negative.In 135 positive cases 84 (62.22%) were male and 51 (37.77% )were female. In 6875 negative cases 2981 were male and 3894 were female. The seroprevalence rate of HBV was 1.93% in mid and far western region in Nepal. Seroprevalence of HBV seems to be higher in male then the female; it was 2.75% in male and 1.29% in female.The study revealed that the seroprevalence of HBV was alarmingly higher in such a population, which probably reflects a high background prevalence of HBV infections should be taken into consideration and Implementation of community-based preventive measures and improved strategies for safe blood supply might prove useful to decrease the seroprevalence.
HYPOALBUMINEMIA: a hospital based study P, Singh; S, Khan; A. H., Siddiqui
INDONESIAN JOURNAL OF BIOMEDICAL SCIENCES Vol 6 No 2 (2012): Indonesian Journal of Biomedical Sciences
Publisher : Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (442.718 KB)

Abstract

Hypoalbuminemia occurs in a variety of disease states and is associated with an increased rate of complications during hospitalization, resulting in an increased length of stay. The purpose of this study is to investigate the prevalence of hypoalbuminemia in IPD and OPD patients and to see which age group and sex have high prevalence of hypoalbuminemia.Nine hundred forty four patients, attending Nepalgunj medical college and Teaching Hospital, Banke, Nepal from March 2011 to February 2012 were included in this study. The normal reference range for serum albumin was 3.5 – 5.5gm/dL in males and females. Hypoalbuminemia is defined as serum albumin < 3.5 gm/dL. The outcome assessments in the hypoalbuminemia and normal albumin groups were compared. Serum albumin level estimation was done by using the diagnostic reagent kit manufactured by RFCL kit , India. A number of 944 studies were selected, the statistical information of which was collected for systematic analysis.The results showed that the high prevalence of hypoalbuminemia found in males (89.72%) as compare to females(88.12%). The prevalence of hypoalbuminemia is different as the period of age and it increases after 21-40 years and high prevalence seen in after the age of 60. Serum albumin level was low in male as compare to female.
Co-Authors Ansari M Khan S Siddiqui A. H.