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Gadjah Mada University
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Hipertensi pada Kehamilan Haidar Alatas
Herb-Medicine Journal: Terbitan Berkala Ilmiah Herbal, Kedokteran dan Kesehatan Vol 2, No 2 (2019): Herb-Medicine Journal Oktober 2019
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/hmj.v2i2.4169

Abstract

Hipertensi pada kehamilan sering terjadi (6-10 %) dan meningkatkan risiko morbiditas dan mortalitas pada ibu, janin dan perinatal. Pre-eklampsia/eklampsia dan hipertensi berat pada kehamilan risikonya lebih besar. Hipertensi pada kehamilan dapat digolongkan menjadi pre-eklampsia/ eklampsia, hipertensi kronis pada kehamilan, hipertensi kronis disertai pre-eklampsia, dan hipertensi gestational. Pengobatan hipertensi pada kehamilan dengan menggunakan obat antihipertensi ternyata tidak mengurangi atau meningkatkan risiko kematian ibu, proteinuria, efek samping, operasi caesar, kematian neonatal, kelahiran prematur, atau bayi lahir kecil. Penelitian mengenai obat antihipertensi pada kehamilan masih sedikit. Obat yang direkomendasikan adalah labetalol, nifedipine dan methyldopa sebagai first line terapi. Penatalaksanaan hipertensi pada kehamilan memerlukan pendekatan multidisiplin dari dokter obsetri, internis, nefrologis dan anestesi. Hipertensi pada kehamilan memiliki tingkat kekambuhan yang tinggi pada kehamilan berikutnya. Hypertension complicates 6% to 10% of pregnancies and increases the risk of maternal, fetal and perinatal morbidity and mortality. Preeclampsia / eclampsia and severe hypertension in pregnancy are at greater risk. Four major hypertensive disorders in pregnancy have been described by the American College of Obstetricians and Gynecologists (ACOG): chronic hypertension; preeclampsia-eclampsia; chronic hypertension with superimposed preeclampsia; and gestational hypertension. The current review suggests that antihypertensive drug therapy does not reduce or increase the risk of maternal death, proteinuria, side effects, cesarean section, neonatal and birth death, preterm birth, or small for gestational age infants. The quality of evidence was low. Recommendations for treatment of hypertension in pregnancy are labetalol, nifedipine and methyldopa as first line drugs therapy. Although the obstetrician manages most cases of hypertension during pregnancy, the internist, cardiologist, or nephrologist may be consulted if hypertension precedes conception, if end organ damage is present, or when accelerated hypertension occurs. Women who have had preeclampsia are also at increased risk for hypertension in future pregnancies.
Studi Epidemiologi Perkembangan Prehipertensi Menjadi Normotensi, Tetap Prehipertensi, Hipertensi Stage I dan Stage II Setelah 10 Tahun HAIDAR Alatas
Herb-Medicine Journal: Terbitan Berkala Ilmiah Herbal, Kedokteran dan Kesehatan Vol 3, No 3 (2020): Herb-Medicine Journal Oktober 2020
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/hmj.v3i3.4392

Abstract

AbstractIndividual with a systolic BP of 120 to 139 mmHg or diastolic BP of 80 to 89 mmHg should be considered as prehypertensive and require health-promoting lifestyle modifications to prevent CVD. After four years, 40% of prehypertension that is not managed properly becomes serious hypertension. Approximately 31–37% of US adults are prehypertensive, is associated with 3-fold greater likelihood of developing hypertension and roughly twice the cardiovascular events. What is the progress of prehypertension after 10 years in rural populations? Will it be normal (normotensive), still prehypertension, become stage I hypertension or stage II hypertension. Epidemiological studies were conducted in Mlati Village, Sleman, Yogyakarta. From the prehypertension subject data as many as 4,091 who were on the computer, after 10 years were selected who were still aged 30-59 years, were willing to take further research and then do interviews and blood pressure checks. The data obtained was analyzed. Of the 743 subjects now aged 30-59 years, who had prehypertension ten years ago, their blood pressure became normal as many as 183 (25%), still prehypertension was 328 (44%), became stage I hypertension as much as 152 (20%) and became hypertensive stage II as many as 80 (11%).  AbstrakPrehipertensi menurut JNC 7 adalah tekanan darah 120-139/80-89 mmHg. Dalam 4 tahun, 40% prehipertensi dilaporkan akan menjadi hipertensi  yang serius bila tidak dikelola dengan baik. Sekitar 31-37% populasi di Amerika Serikat dewasa merupakan  penyandang prehipertensi dan berhubungan dengan kecenderungan tiga kali lipat untuk mengalami hipertensi dan dua kali lipat untuk  mengalami kejadian kardiovaskular dibanding orang dengan tekanan darah normal. Bagaimana perkembangan prehipertensi setelah 10 tahun pada populasi daerah pedesaan? Apakah akan menjadi normal (normotensi), tetap prehipertensi, menjadi hipertensi stage I atau hipertensi stage II. Dilakukan studi epidemiologi di Desa Mlati, Sleman, Yogyakarta. Dari data subyek prehipertensi sebanyak 4.091 yang ada di komputer, setelah 10 tahun dipilih yang masih berusia 30-59 tahun, bersedia mengikuti penelitian lanjutan kemudian dilakukan wawancara dan pemeriksaan tekanan darah. Data yang didapatkan dianalisis. Dari 743 subyek sekarang berusia 30-59 tahun, yang sepuluh tahun lalu prehipertensi, didapatkan tekanan darahnya menjadi normal sebanyak 183 (25%), tetap prehipertensi sebanyak 328 (44%), menjadi hipertensi stage I sebanyak 152 (20%) dan menjadi hipertensi stage II sebanyak 80 (11%). 
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