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All Journal Medical Laboratory Analysis and Sciences Journal
Dian Novita
University of Islam Malang
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology

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In silico studi of Orthosiphon aristatus as antioxidant Dian Novita; Imam Agus Faizal
Medical Laboratory Analysis and Sciences Journal Vol 2 No 2 (2020): November 2020
Publisher : Department of D3 Medical Technology Laboratory STIKes Hutama Abdi Husada Tulungagung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35584/melysa.v2i2.59

Abstract

Orthosiphon aristatus (O. aristatus) is a herbal plant that has antioxidant activity. This study was conducted in a preliminary study of the potential active compound O. aristatus with in silico software pyrex autodock vina method, and visualization using biovia discovery studio. Results from the study in silico showed that O.aristatus extract has potential as an antioxidant compound. Result value of binding affinity with SOD receptor proteins having more negative values compared to control compounds. The interaction of O.aristatus extract is quite potential as an antioxidant, through hydrogen bonding that is equal to control, namely vitamin E
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