Heru Samudro
the Department of Child Health, Christian University of Indonesia Medical School

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Inhaled iloprost as part of combination therapy for persistent pulmonary hypertension of the newborn Heru Samudro; Mulyadi M. Djer
Paediatrica Indonesiana Vol 52 No 1 (2012): January 2012
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (123.616 KB) | DOI: 10.14238/pi52.1.2012.57-60

Abstract

Persistent pulmonary hypertension of thenewborn (PPHN) is rare, but life-threatening.If not treated, PPHN may cause respiratoryfailure and death in neonates. l,2,3 PPHNoften occurs in term or post-term infants with a historyof difficult labor, infection or asphyxia during birth.These infants do not have adequate oxygen duringlabor.3 Based on etiology, PPHN can be categorizedinto primary PPHN, which occurs by itself withoutapparent cause; or secondary PPHN, which is causedby meconium aspiration, hyaline membrane disease,neonatal sepsis with pneumonia, congenital heartabnormality, or maternal drug use (non-steroidalanti-inflammatories, methamphetamine, or selectiveserotonin re uptake inhibitors) during the thirdtrimester of pregnancy.