J. S. Lisal
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Clinical benefits of vitamin A supplementation in infants and children with severe pneumonia Prisca T.; J. S. Lisal; Azis Tanra; Dasril Daud
Paediatrica Indonesiana Vol 47 No 3 (2007): May 2007
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (312.224 KB) | DOI: 10.14238/pi47.3.2007.120-3

Abstract

Background About 190 million preschool children living indeveloping countries are at risk of vitamin A deficiency. VitaminA deficiency and acute respiratory tract infection (ARI) are publichealth problems in developing countries. Children with vitaminA deficiency are more susceptible to measles, respiratory tractinfection, and other infections. Some studies show that vitaminA supplements may reduce the severity of respiratory tractinfection and other systemic complications of measles, anddiarrhea.Objective To evaluate the effect of vitamin A supplementation ininfants and children with severe pneumonia.Methods The study was a randomized trial on children with severepneumonia. Participants were randomly assigned to either receivevitamin A in addition to standard treatment (Group A), orstandard treatment alone (Group C). Time to achieve the normalrespiratory rate, time to achieve disappearance of subcostalretractions and fine rales were compared between the 2 groups.Result There was no significant difference in the achievement ofnormal respiratory rate between the vitamin group and the controlgroup (3.08 days vs 3.29 days). There was also no significantdifference in the disappearance of subcostal retractions amongthe two groups (2.30 days vs 2.48 days). However, there wassignificant difference in the disappearance of fine rales betweenthe two groups. The disappearance of fine rales in the vitamin Agroup occurred earlier (mean 3.72 days) than in the control group(mean 4.04 days) (P<0.01).Conclusions This study indicates that no significant difference inthe achievement of normal respiratory rate and disappearance ofsubcostal retractions between the vitamin A group as comparedto the control group, but there was a significant difference in thedisappearance of fine rales between two groups.
Relationship between newborn mid-upper-arm circumference and birth weight Muhammad Anwar Taufiq; Djauriah A. Madjid; J. S. Lisal; Dasril Daud
Paediatrica Indonesiana Vol 49 No 1 (2009): January 2009
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (123.635 KB) | DOI: 10.14238/pi49.1.2009.11-4

Abstract

Background  Recording  an  accurate  birth  weight  by  primaryhealth care workers has been a problem in rural areas, leadingto a search  for  an alternative, inexpensive, age independent andnoninvasive method to predict neonatal well being. Mid-upper-armcircumference (MUAC) might be  an  alternative anthropometricmeasurement useful  to  estimate the state of nutrition.Objective  To  evaluate  the  relationship  between  MUAC  andbirth weight  in  low birth weight (LBW) and normal birth weight(NBW) infants.Methods  We  measured birth weight and  MUAC  of  newbornbabies  of  various gestational ages  at  Siti Fatimah Maternity  andChildren's Hospital  and  Dr.  Wahidin Sudirohusodo  GeneralHospital, Makassar,  South  Sulawesi, Indonesia.  Correlationtests and diagnostic accuracy using different cut-off points wereperformedResults There were 892 live birth newborns (117 LBW and  775NBW) included in the study.  The  sensitivity, specificity, positivepredictive value, and negative value  for  MUACs  of<  10.3  em  were94.9  %,  99.9%, 99.1%, and 99.2%, respectively.  The  sensitivity,specificity, positive predictive value, and negative value  for  MUAC< 10.4  em  were 99.1  %,  99.6%, 97.5%, and 99.9%, respectively.The  sensitivity, specificity, positive predictive value, and negativevalue for MUAC < 10.5  em  were 100%,99.4%, 95.9%, and 100%,respectively.Conclusion  There  is  a strong correlation between  MUAC  andbirth weight. Birth weight can be predicted with the followingequation: Birth weight= -1776.383  +  (416.95 newborn  MUACvalue).  The  optimal cut-off point  for  the newborn MUAC value  forLBW infants  is<  10.5 em.
Relationship between protein energy malnutrition and urinary tract infection in children Arief Wijaya Rosli; Syarifuddin Rauf; J. S. Lisal; Husein Albar; Dasril Daud
Paediatrica Indonesiana Vol 48 No 3 (2008): May 2008
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (163.975 KB) | DOI: 10.14238/pi48.3.2008.166-9

Abstract

Background Urinary tract infections (UTI) is a common healthproblem in children. Its occurrence depends on several predis-posing factors and individual immunocompetence. Childrenwith protein energy malnutrition (PEM) have impaired immunefunction. Thus early detection and prompt treatment of associatedinfections in children with PEM are very important.Objective To determine the relationship between PEM and theoccurrence of UTI in children.Methods This cross sectional study conducted in Dr. Wahidin Sud-irohusodo Hospital and Labuang Baji General Hospital, Makassarbetween March 1, 2007 and June 30, 2007. The target populationincluded PEM patients aged 2 to 5 years. Well-nourished patientsmatched for age and sex were selected for control group.Results Out of 220 patients, 25 had UTI consisted of 12 malesand 13 females. Eighteen of them had PEM and 7 were well-nourished subjects. There was a statistical significant difference(P=0.019) in the occurrence of UTI between children with PEMand in well- nourished children. The relationship between PEMand UTI as determined by prevalence ratio value (PR) was 2.6with 95% confidence interval (CI) of 1.1 to 5.9, suggested therisk of getting UTI was 2.6 times higher in children with PEM ascompared to normal controls.Conclusions The frequency of UTI in PEM was 16.4%. Chil-dren with PEM have the risk of getting UTI 2.6 times higheras compared to well-nourished children
Plasma lipids as risk factors in relapsing nephrotic syndrome Sitti Aizah Lawang; Syarifuddin Rauf; J. S. Lisal; Husein Albar; Dasril Daud
Paediatrica Indonesiana Vol 48 No 6 (2008): November 2008
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (106.504 KB) | DOI: 10.14238/pi48.6.2008.322-6

Abstract

Background Nephrotic syndrome is primarily a pediatric disorderand is 15 times more common in children than in adults.Relapse rate after corticosteroid discontinuation is 39 - 59%.Hyperlipidemia is an important characteristic of nephroticsyndrome. The plasma concentrations of cholesterol, triglyceride,LDL, and VLDL are increased. Persistent hyperlipidemia afterremission can be found in frequent relapse nephrotic syndrome.Objective To determine plasma lipids as risk factor for relapsingnephrotic syndrome.Methods Thirty children with nephrotic syndrome were includedin this cohort study from March 2005 until June 2007 at WahidinSudirohusodo Hospital, Makassar. Thirty children without renal diseasewere enrolled as control. Blood specimens were collected to determineplasma lipids (cholesterol, triglyceride, LDL, and HDL) levels and LDUHDL ratio. Plasma lipids were examined in the acute and remissionphases. Follow up was carried out six months after remission todetermine the occurrence of relapsing nephrotic syndrome.Results Of 30 nephrotic syndrome patients, 12 had relapsed.There were highly significant differences in total cholesterol, HDL,LDL, triglyceride, and LDL/HDL ratio between acute nephroticsyndrome and nephrotic syndrome in remission. There were nosignificant differences in cholesterol, LDL, triglyceride, LDL!HDL ratio between nephrotic syndrome in remission and control.There was also no significant difference in the incidence in relapsebetween first attack and nephrotic syndrome with more than twoattacks. Acute lipid fraction levels were not risk factors in relapsingmephrotic syndrome. Remission triglyceride level was a risk factorin relapsing nephrotic syndrome with the prevalence risk of 5.2 andCI 95% of 1.06 to 25.3.Conclusion Persistent hypertriglyceride in remission phase isassociated with an increased risk of relapse in children withnephrotic syndrome.