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Guslihan D. Tjipta
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Comparison of blood glucose levels in breastfed vs. formula-fed low birth weight infants Eli Tua Pangaribuan; Bugis M. Lubis; Pertin Sianturi; Emil Azlin; Guslihan D. Tjipta
Paediatrica Indonesiana Vol 49 No 1 (2009): January 2009
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (108.771 KB) | DOI: 10.14238/pi49.1.2009.15-9

Abstract

Background  Low  birth weight infants are defined  as  babies withbirth weight less  than  2500 grams.  Low  birth weight infants tendto suffer from hypoglycemia compared to full term infants.  Theincidence  of  hypoglycemia in newborns varies between 1.3 and  3per 1000 live births. Blood glucose levels in formula-fed infantsare lower  than  those in breastfed infants.Objective  To  compare blood glucose levels in breastfed  andformula-fed low birth weight infants.Methods  A cross sectional study was conducted between February2007  and  June 2007  at  Pirngadi and H. Adam Malik GeneralHospital in Medan,  North  Sumatra, Indonesia. All low birthweight babies were classified into two groups: the breastfed  andformula-fed. Each group consisted  of  32 infants. Capillary bloodwas collected using heel pricks  at  1,  48,  and  72 hours after birth,and plasma glucose was evaluated using the Glucotrend2 bloodglucose test.Results  The  breastfed low birth weight infants had significantlyhigher blood glucose levels (P=0.002)  than  formula-fed low birthweight infants. Mode of delivery  was  related to blood glucose level.Infant delivered  by  caesarean section had significantly differentblood glucose levels  at  1 hour  (P=0.005)  and  72  hours afterbirth (P=0.027).  The  full-term infants had significantly higherblood glucose level (P=0.007)  than  the small for gestational ageinfants.Conclusions  Generally,  low  birth weight infants have hypoglycemiaafter first hour  of  delivery. Breastfed low birth weight infants havehigher blood glucose levels  than  formula-fed low birth weightinfants.
Comparison of blood glucose level between breast--fed and formula--fed term babies Omar Sazali Aldy; Bugis M Lubis; Pertin Sianturi; Emil Azlin; Guslihan D. Tjipta
Paediatrica Indonesiana Vol 48 No 4 (2008): July 2008
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi48.4.2008.209-13

Abstract

Background Hypoglycemia is common in newborns in the firstfew hours after birth. This may also occur in term babies. Dataof hypoglycemia in breastfed and formula-fed infants have beenlimited.Objective To compare blood glucose levels between breast-fed andformula-fed healthy term babies at 1, 24 and 48 hours of life.Methods A cross sectional study was performed on 32 neonatesbetween January and March 2007 in the Dr. Pirngadi Hospital.The subjects was classified into two groups, the breastfed andformula-fed groups. Blood glucose level was examined at 1, 24,and 48 hours after birth and level ofless than 2.6 mmol/1 definedthe presence of hypoglycemia.Results There was statistically significant difference in meanblood glucose level at 1 hour of life between breastfed [59.25(SD 3.38) mg/dl] and formula-fed infants [55.96 (SD 8.60) mg/dl], (P=0.049), while no significant difference was found after24 hours of life, i.e., 62.59 (SD 3.57) mg/dl vs. 61.21 (SD 6.87)mg/dl, P=0.319 and also after 48 hours of life, i.e., 67.34 (SD5.18) mg/dl vs. 66.75 (SD 7.76) mg/dl, P=0.720.Conclusion The blood glucose level at one hour after birth wassignificantly different in breastfed compared to formula-fed infants,while no statistically significant difference was found at 24 hoursand 48 hours after birth. The mean blood glucose at 24 hours oflife was lower than that of 48 hours after birth
Comparison of the effect of oral multiple dose with single intramuscular vitamin K1 administration on prothrombin time in term baby Nancy Ervani; Bugis M. Lubis; Emil Azlin; Guslihan D. Tjipta; Lily Emsyah
Paediatrica Indonesiana Vol 49 No 5 (2009): September 2009
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (104.26 KB) | DOI: 10.14238/pi49.5.2009.281-5

Abstract

Background Vitamin K deficiency can cause bleeding disorders inhealthy breastfed infants. The efficacy of newborn intramuscularvitamin K prophylaxis for the prevention of this bleeding problemhas been well established, but this is an invasive procedure. Oralvitamin K prophylaxis is more effective, less expensive, and lesstraumatic than intramuscular administration.Objective To compare prothrombin time (PT) after theadministration of oral multiple dose vitamin K1 with that afteran intramuscular preparation.Methods Infants were randomised at birth into the intramuscular(IM) group (1 mg vitamin K1) and the oral group (2 mg given atbirth and repeated at day 3). PT was monitored before and afterthe administration of vitamin K1.Results Thirty six of 70 infants received oral vitamin K1. MeanPT (SO) before vitamin K1 administration was 36.34 (SO 20.03)seconds in oral group and 31.96 (SO 25.51) seconds in IM group, PT changes after vitamin K1 administration were 16.29 (SO 15.46) seconds in oral group and 11.58 (SO 10.62) seconds in IM group, it did not differ significantly (P=0.203).Conclusion Prothrombin time changes are not significantlydifferent between oral vitamin K1 and IM group.
Co-Authors Bugis M Lubis Bugis M. Lubis Eli Tua Pangaribuan Emil Azlin Lily Emsyah Nancy Ervani Omar Sazali Aldy Pertin Sianturi