M. Ikhwan Setiawan
Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

PENGARUH KOMBINASI EKSTRAK ETANOL KULIT PUTIH BUAH SEMANGKA (CITRULLUS LANATUS (THUNB.)) DAN AIR BONGGOL PISANG KEPOK (MUSA ACUMINATA X MUSA BALBISIANA (ABB GROUP)) TERHADAP PERTUMBUHAN RAMBUT TIKUS PUTIH JANTAN M. Ikhwan Setiawan; Anna P. Roswiem; Ika Wahyu Pertiwi
Jurnal Farmamedika (Pharmamedika Journal) Vol 3 No 2 (2018): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (295.278 KB) | DOI: 10.47219/ath.v3i2.12

Abstract

White skin of watermelon and the liquid of kepok banana tree trunk empirically widely used as hair growth, In addition ethanol extract white skin of watermelon and the liquid of kepok banana tree trunk has also been scientifically proven able to accelerate the growth hair of the rat. However the research activity of the combination of the two against the hair growth has never done. The purpose of this research is to know the combination of both these extracts which can give of the most activity is good for hair growth. Ethanol extract of white skin of watermelon extraction is done by of maceration using a solvent of ethanol 70 %, as for getting the test sample is liquid of kepok banana tree trunk done by cutting down banana tree trunk approximately 50 cm above the ground surface then the stem of banana leaf his satin-the core then covered with plastic and silenced for one night. The results showed that the combination of liquid of kepok banana tree trunk and Ethanol extract white skin of watermelon (2:1) have a long hair growth activity higher than the positive control (Minoxidil), While hair growth activity of weights lower than the positive control (Minoxidil)
PREPARASI DAN KARAKTERISASI NANOPARTIKEL KITOSAN MENGANDUNG ANTIGEN INTI HEPATITIS B (HBcAg) DARI Escherichia coli BL21 (DE3) M. Ikhwan Setiawan; Chaidir; Deni Rahmat; Asrul Muhamad Fuad
Jurnal Farmamedika (Pharmamedika Journal) Vol 9 No 1 (2024): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47219/ath.v9i1.368

Abstract

Hepatitis B Core Antigen (HBcAg) adalah antigen struktural dari virus hepatitis B yang berpotensi menjadi senyawa aktif dalam vaksin hepatitis B. Dalam penelitian ini, HBcAg dihasilkan melalui biosintesis protein rekombinan dari Escherichia coli BL21 (DE3). Selanjutnya nanopartikel HBcAg disiapkan dengan metode gelasi ionik menggunakan crosslinker kitosan (CHI) dan natrium tripolifosfat (STPP). Analisis menggunakan Particle Scanning Analyzer menunjukkan bahwa nanopartikel terkecil sebesar 126,4 nm diperoleh dari perbandingan 2:1 kombinasi kitosan 0,1% dan STPP 0,1%, sementara kombinasi 5:3 menghasilkan keseragaman nanopartikel terbaik dengan indeks polidispersi 0,319. Stabilitas nanofluida terbaik diperoleh dari kombinasi 2:1 kitosan 0,15% dan STPP 0,1% dengan nilai zeta-potensial 22,2 mV. Efisiensi penangkapan tertinggi sebesar 94,26% diperoleh pada rasio 4:3 CHI:STPP. Uji pelepasan antigen in vitro menunjukkan bahwa pelepasan protein dari struktur nanopartikel lebih rendah dalam larutan asam dibandingkan dalam larutan basa