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Cholid Rasidi
Department of Child Health, University of Indonesia Medical School, Jakarta
Health Professions Medicine & Pharmacology

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Indomethacin Therapy in Premature Infants with Patent Ductus Arteriosus Cholid Rasidi; Bambang Madiyono; Ismeet N. Usman
Paediatrica Indonesiana Vol 22 No 3-4 (1982): March - April 1982
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (490.293 KB) | DOI: 10.14238/pi22.3-4.1982.70-6

Abstract

Indomethacin has been shown to be effectil'e in closing patent ductus arteriosus (PDA) in premature infants. Indomethacin admin.istration decreased the need for assisted ventilation and surgical closure of PDA. Six premature neonates with birth weight less than 2500 gm diagnosed clinically as PDA were given indomethacin. The drug was given as a single dose by mouth or nasogaYtric tube in 2 or 3 consecutlve days. The dose in the first two days was 0.1 mg/kg BW and the last dose (If necessary) was- 0.3 mg/kg BW. Closure of PDA was observed in all six cases. This experience in the use of indomethacin in PDA indicates a need for a further study of the effect of indomethacin in PDA.
Co-Authors Bambang Madiyono Ismeet N. Usman