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Ediyono Ediyono
Department of Child Health, Universitas Gadjah Mada Medical School/Dr. Sardjito Hospital, Yogyakarta, Central Java
Health Professions Medicine & Pharmacology

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Types of allergen affecting asthmatic children M. P. Damanik; A. Samik Wahab; Ediyono Ediyono; Ismangoen Ismangoen
Paediatrica Indonesiana Vol 24 No 7-8 (1984): July - August 1984
Publisher : Indonesian Pediatric Society

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Abstract

An intracutane tuberculin test with several types of allergens was conducted on 110 asthmatic children under the age of 14 years at the Subsection of Allergic diseases and Immunology of the Internal Diseases Section, in cooperation with the Department of Child Health, Gajah Mada University, Pugemn Hospital, in Yogyakarta. The number of children found to be sensitive to house dust, human dander, grass pollen, fungus, collection of animal danders, "mite" (Pteronysinus pterygoideus), and bacteria vaccine were 82 (75,5%), 80 (72. 7%), 0 (0%), 3 (2. 7%), 1 (0,9%), 23 (20.9%), and 20 {18.1%), respectively. It was also found that four ( 3.6%) of the children did not develop any reaction to all allergen types. It was further concluded that the numbers of children being allergic to just one type of allergen were as follows : house dust 2 (1.8%); human dander 0 (0%), hence all patients allergic to the human dander were also allergic to house dust; fungus 1 (0.9%); collection of animal danders 1 (0.9%); "mite" 2 (1.8%); bacteria 19 (17.3%). The highest incidence of reaction to more than one allergen were to house dust+human dunders: 80 (72. 7%); to house dust+ "mite": 21 (21.91%); and to house dust+human dander +"mite": 17 ( 15.5%).
The Influence of Desensitization on The Recovery of Allergy, In articular Asthma M. P. Damanik; A. Samik Wahab; Suminta Suminta; Ediyono Ediyono; Ismangoen Ismangoen
Paediatrica Indonesiana Vol 24 No 9-10 (1984): September - October 1984
Publisher : Indonesian Pediatric Society

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An evaluation was carried out to determine the effect of desensitization on 62 asthmatic patients under the age of 14 years. Preceeding the evaluation, an intracutaneous skin test was conducted of which all patients produced positive reactions to one or more allergen types. Desensitization was carried out for at least 5 months (up to the 30th injection), .with the following results : good, 45 (72,57%); decreased symptoms 12 ( 19.03%), and constant (no change), 5 (8,4%). All patients reached the maximum dosage ( 1 cc ), except 2 patients whom, given the maximum dosage, become worse, therefore suitable dosages were maintained (0.5 - 0. 7 cc). Therapy for one type of allergen was also proven as follows: house dust, good 1 (100%); mite, good 1 (100%); bacteria, good 14 (87.5%), fungi, good 1 (100%). Result of therapy for 2 types of allergen : f' , use dust +splinter of human dunder in 31 patients was : good 24 (77.4%); constant 7 (22.59%). Whilst therapy for 3 types of allergen : house dust + splinter of human dunder + mite revealed : good, 4 (33.4%); decreased symptoms, 3 (25%); and constant, 5 (41.6%). It may therefore be concluded that the greater the number of allergens, the less effective the desensitization becomes.
Co-Authors A. Samik Wahab Ismangoen Ismangoen M. P. Damanik Suminta Suminta