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Sunoto Sunoto
Department of Child Health, Universitas Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta
Health Professions Medicine & Pharmacology

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Persistent Diarrhea: Possible Risk Factors in Indonesia Sunoto Sunoto
Paediatrica Indonesiana Vol 33 No 5-6 (1993): May - June 1993
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (697.47 KB) | DOI: 10.14238/pi33.5-6.1993.126-32

Abstract

From the management point of view, acute diarrhea in Indonesian children is not a big problem anymore. Persistent diarrhea, although the prevalence is less than 10% of acute diarrhea, hut the case fatality rate is about 5-7 times higher which is account for 30-50% of total diarrhea deaths. There are many factors which may contribute to the etiologies of persistent diarrheas. They are among others the specific agents mainly the invasive bacterias (Galmonella spp, Shigella spp, Campylobacter spp, Enteroinvasive E. coli, etc.), Giardia Lamblia and E. histolytica; malnutrition, malabsorption syndromes, systemic infections mainly measles; and last but not least the missmanagement of acute diarrhea, particularly the abundance use of antibiotics and antidiarrheal agents, the late of giving food to the patients and the too early giving semisolid food in normal young baby less than 4-6 month of age.
Oral Rehydration Therapy in Young Infants less than 3 Months with Acute Diarrhoea and Modeate Dehydration Sunoto Sunoto; Suharyono Suharyono; Aswitha D. Budiarso; Adnan S. Wiharta
Paediatrica Indonesiana Vol 28 No 3-4 (1988): March - April 1988
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (822.753 KB) | DOI: 10.14238/pi28.3-4.1988.67-78

Abstract

Oral rehydration therapy (ORT) as an appropriate technology in the treatment of acute diarrhoeal diseases (ADD) has been accepted throughout the world. It has been proved that besides lifesaving, ORT has reduced about 70-80% of the use of intravenous solution and average cost of the treatment of ADD. If there is still problem, question or doubtfulness, is the use of WHO ORS in full concentration for the neonates and young infants less than 3 months of age. During one-year period it has been treated 72 cases of ADD in young infants less than 3 months of age with moderate dehydration. They were divided into 3 groups. The first group was treated with 100 mil kg bw of fluid consisting oftwothirds as WHO ORS in full concentration for 4 hours period and the rest, one-third, was given as plain water for 2 hours period. The second group was treated with kristalyte with the Na concentration of 51 mEq/L and the third group was treated with intravenous Ringer's lactate for 6 hours period. After the end of the study only 18 patients in each group could be matched and evaluated. From clinical observation and laboratory examinations, the result of the treatment in general, statistically shows no significant difference. Diarrhoea and vomiting stopped in all groups on the second day of treatment. Hyponatremia which occurred in 3 patients in Group I and 2 patients each in Group II and III improved after 6 hours of treatment. Acidosis was corrected in all of the treatment groups in 6 hours period. Weight gain up to 6-9% of body weight on admission was achieved after 6 hours of treatment in all groups. No complication of hypernatremia, convulsion nor hypoglycaemia in all the treatment group. From this study it could be concluded that WHO ORS is quite safe and effective as ORS with low sodium concentration and intravenous treatment, as far as it is given slowly, little by little with a strict supervision.
Tiberal (Ro 7-0207-Roche) in the Treatment of Intestinal Amoebiasis - Part II Sunoto Sunoto; S. H. Pudjiadi; Suharjono Suharjono; Z. Sulaiman
Paediatrica Indonesiana Vol 16 No 9-10 (1976): September - October 1976
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (584.836 KB) | DOI: 10.14238/pi16.9-10.1976.403-11

Abstract

Twenty-four intestinal amoebiasis patients have been treated with a new amoebicid tiberal (Roche) or metronidazole as a control in a dosage of 15- 30 mg/kg body weight per day for 5 consecutive days. The results show that both drugs achieve a 100% cure rate. No side effects or signs of drug toxicity as evaluated from the results of the safety tests were observed. No signs of clinical or parasitological relapses were seen (after discharge. In comparison with the previous trial with a lower dosage (7~ - 15 mg.) and longer course (7 days) the results were even better, e.g. clinical improvement and parasitological disappearance were achieved in a shorter time.
Co-Authors Adnan S. Wiharta Aswitha D. Budiarso S. H. Pudjiadi Suharjono Suharjono Suharyono Suharyono Z. Sulaiman