Article Per Year (5 Year)
p-Index From 2020 - 2025
0.23
P-Index
This Author published in this journals
All Journal FITOFARMAKA: Jurnal Ilmiah Farmasi
Yulianita .
Unknown Affiliation
Chemistry Medicine & Pharmacology

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
UJI AKTIVITAS EKSTRAK ETANOL 96% DAN FRAKSI DAUN KIRINYUH (Chromolaena odorata L.) TERHADAP PROPIONIBACTERIUM ACNES Oom Komala; Yulianita .; Rita Rahmawati
FITOFARMAKA: Jurnal Ilmiah Farmasi Vol 11, No 1 (2021): FITOFARMAKA | Jurnal Ilmiah Farmasi
Publisher : Universitas Pakuan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33751/jf.v11i1.2657

Abstract

Chromolaena odorata L. leaves can be used as an antibacterial because of contain flavonoid compounds. The secondary metabolite content of Chromolaena odorata L leaves include flavonoids, tannins, saponins, and steroids which have antibacterial activity. The aim of this study was determine the antibacterial activity of  ethanolic 96% and fraction of Chromolaena odorata L leaves and determine the concentration of  Chromolaena odorata L fraction and ethanol 96% extract which was most effective as an antibacterial against Propionibacterium acnes. The method was used to determine the MIC was a solid dilusion method, while the determination of inhibitory zone by the paper disk diffusion method at concentrations of 10%, 15% and 20% in each sample. The MIC showed hexane fraction is 15%, ethylacetate fraction is 15% and water fraction is 10%. The best antibacterial activity in the ethylacetate fraction and ethanol 96% extract  at a concentration of 20% with the width of the zone of inhibition values of 4.375 mm and 4 mm.
Co-Authors Oom Komala Rita Rahmawati