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All Journal FITOFARMAKA: Jurnal Ilmiah Farmasi
Gelline Tama Anindia Firman
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Chemistry Medicine & Pharmacology

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AKTIVITAS HEPATOPROTEKTOR KOMBINASI EKSTRAK AIR PEGAGAN (Centella asiatica L. Urban) DAN EKSTRAK ETANOL KUNYIT (Curcuma longa Linn) TERHADAP TIKUS PUTIH JANTAN SPRAGUE DAWLEY Gelline Tama Anindia Firman; Min Rahminiwati; Ike Yulia Wiendarlina
FITOFARMAKA: Jurnal Ilmiah Farmasi Vol 7, No 1 (2017): Fitofarmaka Jurnal Ilmiah Farmasi
Publisher : Universitas Pakuan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (736.457 KB) | DOI: 10.33751/jf.v7i1.797

Abstract

ABSTRAKHepatoproktektor adalah senyawa yang dapat mencegah dan memperbaiki sel-sel hepar yang rusak. Parameter yang diamati adalah perubahan kadar SGPT pada hari ke 0,2, 5, 9 dan 13. Hasil penelitian dari 9 kombinasi dosis selama 13 hari menunjukkan semua kombinasi menurunkan kadar SGPT dengan aktivitas hepatoprotektor terbaik adalah terdapat pada tumbuhan ektrak air pegagan: ekstrak etanol kunyit dengan perbandingan 2:3.Kata kunci: Pegagan (Centella asiatica L.Urban), Kunyit (Curcuma longa Linn) dan hepatoprotektorABSTRACTHepatoprotector is a compound that can prevent and repair liver cell damage. This research aimed to study the activity and effectivity of combination Centella asiatica water extract and Curcuma longa ethanol extract as hepatoprotector by SGPT (Serum Glutamat Piruvat Transaminase) in Sprague Dawley male white rats induced paracetamol. Parameters measured were changes in ALT levels at day 0, 2, 5, 9 and 13. Combinations of doses for 13 days showed all combinations of those extract potencial hepatoprotector. The best activity was found in ratio 2:3 (Centella asiatica extract:ethanol extract of turmeric).Keywords: Centella asiatica L. Urban, Curcuma longa Linn and Hepatoprotector
Co-Authors Ike Yulia Wiendarlina Rahminiwati, Min