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All Journal MAHESA : Malahayati Health Student Journal Journal of General Procedural Dermatology and Venereology Indonesia
Widodo J. Pudjirahardjo
Departemen Administrasi dan Kebijakan Kesehatan Fakultas Kesehatan Masyarakat Universitas Airlangga Surabaya
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

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Cumulative exposure to solar ultraviolet A & B increases apoptosis of peripheral blood cutaneous lymphocyte antigen (CLA)+ T-Lymphocytes in outdoor workers Hidayati, Afif Nurul; Pohan, Saut Sahat; Pudjirahardjo, Widodo J.; Effendy, Isaac
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 3, No. 1
Publisher : UI Scholars Hub

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Background: Exposure to ultraviolet A & B (UVA-UVB) plays a role in the survival of human life, but it may cause negative effects, such as immunosuppression and skin cancer. The effect of solar UVA-UVB exposure on apoptosis (Bax/Bcl-2 ratio) of peripheral blood cutaneous lymphocyte antigen (CLA)+ T-lymphocyte; the immune competent cells in the skin, has not been investigated. Apoptosis of peripheral blood CLA+ Tlymphocyte affects its function; which serves as the skin's resistance and is involved in infectious diseases, skin inflammation, and malignancies. This study observed the effect of solar UVA-UVB to apoptosis (Bax/Bcl2 ratio) of peripheral blood CLA+ T-lymphocytes. Methods: An observational cohort study of 37 male outdoor workers (caddies on the golf course) and 33 indoor workers in Surabaya, aged 20-45 years, with skin phototype IV/V. Measurement of solar UVA-UVB doses received by the subjects was conducted for 2, 4, and 8 weeks. Examination of Bax and Bcl-2 of peripheral blood CLA+ T-lymphocyte was conducted at the beginning of the study, after 4 and 8 weeks. Results: The average dose of solar UVA-UVB for 8 weeks received by outdoor workers was 12450.51±3948.81 (J/m2 ) and that by indoor workers was 1793.97±1518.46 (J/m2 ). Exposure to solar UVAUVB leads to the increase of apoptosis (Bax/Bcl-2 ratio) of peripheral blood CLA+ T-lymphocytes (p=0.003). Conclusion: Cumulative exposure to solar UVA-UVB radiation in high-dose or received within 8 weeks resulted in the increase in apoptosis of peripheral blood CLA+ T-lymphocytes.
Analysis of The Influence Brand Image on Community Purchase Intention in Outpatient Services at Bima City Hospital Dimara, Fransiska Natalia; Nurhidayati, Restu; Wulandari, Ratna Dwi; Pudjirahardjo, Widodo J.
MAHESA : Malahayati Health Student Journal Vol 5, No 5 (2025): Volume 5 Nomor 5 (2025)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v5i5.17137

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ABSTRACT Hospitals face competitive competition due to open market policies in the medical services industry. In the realm of health services, brand image plays an important role in determining patient purchase intentions. Therefore, the aim of this study is to analyze the influence brand image on community purchase intention in outpatient services in government hospitals. An analytical study with a cross-sectional approach was was carried out by distributing questionnaires in Bima from October 2022 to July 2023. The population of this study were people related to hospital services with good awareness and aged 19 -60. The sample was selected using the proportional stratified random sampling method. Descriptive statistics and correlation analysis were used to analyze the data. A total of 260 respondents from five sub-districts participated in the study. The results showed that brand image had a significant effect on the community's purchase intention towards outpatient services. Influential brand image indicators are type of brand associations with value (p = 0.486 b = 0.001), favorability of brand association with value (p = 0.198 b = 0.001) and uniqueness of brand associations with value (p = 0.165 b = 0.001). A good brand image can increase purchase intention. The brand image sub-variable that has the greatest influence on purchase intention is the type of brand associations. There was one item that was rated as poor by 60.4% of respondents regarding the timeliness of doctor services in outpatient care. A good brand image can increase purchase intentions. Evaluation and coordination between management and service providers are necessary to improve the hospital's brand image. Related activities and service schedules of doctors in the hospital must be well organized so that there is no doctor's absence. Keywords: Brand Image, Hospital, Outpatient Service, Purchase Intention
Co-Authors Afif Nurul Hidayati, Afif Nurul Dimara, Fransiska Natalia Effendy, Isaac Nurhidayati, Restu Ratna Dwi Wulandari Saut Sahat Pohan