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All Journal Jurnal Farmasi Galenika (Galenika Journal of Pharmacy)
Mia Fitriana
Universitas Lambung Mangkurat, Banjarmasin, Kalimantan Selatan
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology

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AKTIVITAS SEDIAAN GEL KUERSETIN TERHADAP Staphylococcus Epidermidis Rina Apriana Herslambang; Dina Rahmawanty; Mia Fitriana
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 1 No. 1 (2015): (March 2015)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (463.942 KB) | DOI: 10.22487/j24428744.2015.v1.i1.7901

Abstract

Acne is the abnormality production of sebum in the sebaceous glands which are usually caused by Staphylococcus epidermidis. Staphylococcus epidermidis one of bacterial that caused acne. Quercetin have a phenolic compound that can inhibit the growth of Staphylococcus epidermidis at 0.05% w/w. The purpose of this study was to determine the minimum inhibitory concentration of quercetin gel. HPMC was used as gel base. The concentrations of quercetin that was added to gel were 0.05% w/w, 0.15% w/w, and 0.25% w/w. The antibacterial activity of the gels was determined using agar diffusion method. The results showed that the inhibition zone on the F1, F2, and F3 were 7.83 mm , 6.53 mm , 4.56 mm and the result showed that quercetin gels significantly effected the growth of Staphylococcus epidermidis (p<0,05). The minimum inhibitory concentration of quercetin gel was 0,05% w/w with inhibition zone of 7.83 mm.
Co-Authors Dina Rahmawanty Rina Apriana Herslambang