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Katiko Imamul Muttaqin
Department of Mechanical and Industrial Engineering, Faculty of Engineering, Universitas Gadjah Mada. Jl. Grafika 2, Yogyakarta 55281, Indonesia
Engineering Industrial & Manufacturing Engineering Mechanical Engineering

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Chitosan-Curcumin Coating Characterization on Cobalt-Chrome Surface by 100 kHz Ultrasonic Spray Method Katiko Imamul Muttaqin
Journal of Material Processing and Characterization Vol 1, No 2 (2020): Articles
Publisher : Departmen Teknik Mesin dan Industri, Fakultas Teknik, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (367.611 KB) | DOI: 10.22146/jmpc.68281

Abstract

Curcumin possesses anticoagulant, anti-proliferative, and anti-inflammatory properties and is applicable to prevent in-stent restenosis. This research investigated curcumin coating with biodegradable chitosan polymer as a drug carrier universally made on Co-Cr L605 surface by the ultrasonic spray method. Three curcumin doses were implemented: low dose (150 μg of curcumin per sample), medium dose (300 μg of curcumin per sample), and high dose (480 μg of curcumin per sample). The metal surface morphologies before and after coating were examined by using a stylus profilometer and a scanning electron microscope (SEM). The result showed that coating films were formed fine and uniform with an average roughness level below 0.2 μm. The coating film structure characterization by Fourier-transform infrared (FTIR) spectroscopy showed that curcumin absorption spectra still occurred in the chitosan-curcumin coating, although chitosan strong absorption spectra were dominant.
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