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All Journal Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)
Herlambang Noerjasin
Bagian Obstetri dan Ginekologi Fakultas Kedokteram Universitas Sriwijaya/Rumah Sakit M. Husin, Palembang
Health Professions Medicine & Pharmacology Public Health

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The correlation between serum protein Bcl-2 and caspase 3 levels as a risk factor in abortion Herlambang Noerjasin
Indonesian Journal of Obstetrics and Gynecology Volume. 34, No. 1, January 2010
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To determine the correlation between serum protein Bcl-2 with caspase-3 levels on normal pregnancy and abortion, and the strength of serum protein Bcl-2 with caspase-3 levels as means for diagnostic test. Methods: A case control study was carried out. Samples were obtained from the serum of incomplete abortion patients and normal pregnancy as control. Serum protein Bcl-2 and caspase-3 levels were examined with ELISA method. Result: Mean Bcl-2 level in subjects with abortions is 7.263 (SD 1.71) ng/ml, lower than normal pregnancies, which is 7.490 (SD 3.938) ng/ml, with significant different (p=0.050). Mean caspase-3 in subjects with abortions is 112.74 (SD 152.73) mg/ml, higher than normal pregnancies, which is 14.94 (SD 23.18) mg/ml, with significant different (p
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