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All Journal Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)
Gregorius Tanamas
Faculty of Medicine University of Indonesia/Dr. Cipto Mangunkusumo HospitalJakarta
Health Professions Medicine & Pharmacology Public Health

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Risk of Malignancy Index is not accurate as a Triage Tool for Ovarian Cancer Gregorius Tanamas; Jasmine Iskandar; Tofan W Utami; Tricia D Anggraeni; Kartiwa H Nuryanto
Indonesian Journal of Obstetrics and Gynecology Volume. 2, No. 1, January 2014
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (110.17 KB) | DOI: 10.32771/inajog.v2i1.380

Abstract

Objective: To evaluate Risk of Malignancy Index (RMI) as a triage tool for ovarian cancer in Dr. Cipto Mangunkusumo Hospital. Method: This is a retrospective study conducted from January 2008-December 2012 in patients diagnosed with ovarian mass. Patients admitted for surgery due to ovarian masses were included to this study. RMI 3 score was calculated based on ultrasonography examination in Dr. Cipto Mangunkusumo Hospital, CA-125 test and menopausal status. Patients without final pathological report and incomplete data were excluded from study. Data were analysed using SPSS 20 to evaluate RMI result and final pathlogical report in benign and malignant case. Result: From 882 patients identified with ovarian masses from cancer registry, only 99 patients aged 17-70 y.o were included in this study. Most of the patients were nully-parity (28.3%), non-menopausal women (60.6%), normal body mass index (40.4%), and with stage IIIC ovarian cancer (33.3%). Ultrasonography examination showed that most of patients had solid mass and ascites (19.2%). Meanwhile, CA-125 showed that patients with <35 U/ml were 10.1% and ≥ 35 U/ml were 89.9%. Patients with RMI scores <200 (benign cases) were 19 cases (19.2%) and ≥ 200 (malignant cases) were 80 cases (80.8%). Meanwhile, patients with benign final pathological report were 23 cases (23.2%) and malignant cases were 76 cases (76.8%). There was no statistical difference in RMI between benign and malignant cases based on final pathological report. Conclusion: Our study showed that RMI was not accurate as triage tool for ovarian cancer in our hospital. Further investigation and more patients are needed to confirm this study. Keywords: CA-125, menopausal status, ovarian cancer, risk of malignancy index (RMI), ultrasonography.
Higher Preoperative Endometrial Cancer Risk Showed More Advanced Stage Jasmine Iskandar; Gregorius Tanamas; Tofan W. Utami; Tricia D. Anggraeni,;  Kartiwa H. Nuryanto
Indonesian Journal of Obstetrics and Gynecology Volume. 2, No. 2, April 2014
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (135.837 KB) | DOI: 10.32771/inajog.v2i2.391

Abstract

Objective: To evaluate the pr eoperative endo metria l cancer risk as a guida nce to choose th e typ e of surg ical approach based on European Society for Medical Oncology guideline (200 9). Method: Cross-sectional study involved 73 endometrial cancer patients of Dr. Cipto Mangunkusumo Hospital, from january 200 6 to December 2012 whi ch obt ain ed from medical record. The inclusion criteria wer e endometr ial cancer pati ents with compl ete D&C, ultr asonographic, and postoperative histopathological rep orts. Endometrial cancer risk of recurren ce was classified acco rding to ESMO 2009 and final diagno sis and stage based on FIGO. Result: From 40 5 patients, only 73 patients had compl ete reports. Most of the them were postmenopaus al (54.8 %), non-nulliparity (79 .9%), and obese (49.5%) women.According to risk of recurren cestratification, low, intermediate and high risk were found in 12 patients, 27 patients, and 34 pati ents. Based on FIGO, there were 60.2% early and 39.8% advanced sta ge. In high risk gro up, rates of advan ced stage wer e prominent compar ed to othe r gro ups. There were 38.3% patients with postoper ativ e positive lymph nod es metastases. Conclusion: Most of th e endometrial cancer patients we re pr eoperatively diagnosed as high risk. The commones t stage after surgical examination were me. High risk of recurrence showed more positive lymph node compared to low or intermediat e risk. Result of preoperative histopathological and myometrial invasion compared to postoper ative results wer e showed to be inconsistent Pat ients with =1/2 myometrial invasion had more positive lymph nodes metastases. Endometrial cancer risks compared to FIGO stage showed the higher the risk, th e more advanced the stage were. Keywords: endometrial cancer, FIGO stage, high risk, histol ogical type, intermediate risk , low risk, lymph node.
Co-Authors  Kartiwa H. Nuryanto Jasmine Iskandar Kartiwa H Nuryanto Tofan W Utami Tofan W. Utami Tricia D Anggraeni Tricia D. Anggraeni,