Jeni Poniman
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EKSPRESI PROGESTERONE RECEPTOR (PR) PADA BENIGN, ATYPICAL DAN ANAPLASTIC MENINGIOMA Jeni Poniman
Alami Journal (Alauddin Islamic Medical) Journal Vol 4 No 1 (2020): JANUARY
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (220.77 KB) | DOI: 10.24252/alami.v4i1.10092

Abstract

ABSTRAKBackground: Meningioma is the most common brain tumour in adult which treatment and follow-up depend on the histologic grade. Aim: This research aim is to assess the difference of Progesterone Receptor (PR) expression in 3 grade groups meningioma which are benign, atypical and anaplastic meningioma. Method: It is an analytic observational research with cross sectional design using immunohistochemical staining of PR antibody on 30 samples of paraffin blocks. Result: PR immunostaining positive in benign and atypical meningioma, and PR immunostaining negative in anaplastic meningioma with p value less than 0.05 (p = 0.000). Conclusion: There is difference of PR expression in each meningioma grade groups; benign, atypical and anaplastic meningioma.Key Words: progesterone receptor, meningioma